Illinois football kicked off 2026 with a dominant win over UAB, setting the stage for a high-stakes showdown against Duke. The Illini are favored by 6.5 points, and with Katin Houser leading the charge and the defense stepping up, they’re primed to cover. While the money line leans heavily on Illinois, the payout isn’t worth the risk. The over/under sits at 53.5 — and despite both teams’ offensive questions, the Illini’s disciplined play and Duke’s shaky start suggest this one will go under. Expect Illinois to score in the 20s, but Duke won’t keep pace — it’s a battle, but the Illini are looking strong from day one.
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