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Key Moments:

0:00 Introduction

3:02 Founding Story: Connectome Health

6:15 Inspiration for Company Name: Connectome Health

8:12 fNIRS Overview and Connectome’s Modality Agnostic Strategy

10:23 Hardware

11:26 Key Brain Metrics

13:16 Goal to Move into NeuroDiagnostics

13:59 Scientific Validity and Research Behind Connectome’s Metrics

15:27 Strategy to Eventually Enter Clinical Space

18:07 Connectome User Experience 

25:44 Current State of Connectome Health: Pre-Launch, Fundraising 

27:02 Long-Term Vision for Connectome Health

29:47 Advice for Students or Young Professionals Interested in Neurotech

30:56 The Future of Neurotechnology

33:41 Book/Media Recommendations: Huberman Lab, Being You (by Anil Seth), The Spike (by Mark Humphries), The Old Man and The Sea (by Ernest Hemingway)

35:40 Conclusion

Connectome Health: https://www.connectome.health/

Recorded: 4/17/2025

Host: Robert Murcko 

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Key Moments:

0:00 Introduction: University, First Startup, Corporate Experience

2:44 Initial Interest in AI and Neuroscience 

4:24 Founding Story of Piramidal

5:49 Y Combinator: Learnings and Experiences

7:35 Product: Foundation Model for the Brain

9:47 Competitive Landscape

12:05 Short Term Vision, Long Term Vision, Place within Neurotech Ecosystem

13:09 Day-to-Day as Neurotech Startup Executive

14:19 Entrepreneurship Lifestyle

15:05 Corporate Lessons for the Startup World

15:58 Advice for Breaking into Neurotech and Startups

17:02 Predictions for the Future of Neurotechnology

17:43 Book Recommendation: A Year in Provence

18:32 Conclusion and Contact Information

Piramidal: https://piramidal.ai/

Recorded: 8/1/2024

Host: Robert Murcko

Free Neurotech Newsletter: https://neurotechnologynews.beehiiv.com/subscribe

Key Moments:

0:00 Introduction

3:17 Initial Interest in Neuroscience

4:50 Origin Story of Reach Neuro

6:16 Reach Neuro’s Avantis Platform

11:12 Reach Neuro Competitors

14:40 Navigating FDA Regulations and Breakthrough Device Designation

19:02 Research Tools and Product Development Feedback Loops

20:46 What is Next for Reach Neuro?

22:49 Algorithms and Spinal Anatomy

24:51 Breaking into Neurotech: Advice for Aspiring Professionals

26:28 The Jump from Academia to a Startup in Neurotech

28:14 The Future of Neurotechnology

30:56 Conclusion and Contact Information

Recorded: 2/7/2024

Host: Robert Murcko 

Free Neurotech Newsletter: https://neurotechnologynews.beehiiv.com/subscribe

Key Moments:

0:00 Introduction

3:23 Initial Interest in Neuroscience/Neurotechnology

5:10 Neurovalens: Background, Timeline, Origins

7:52 Clinical Trials: Insomnia, Anxiety, Obesity, PTSD, Diabetes 

8:40 Neurostimulation: Type and Target

10:40 Exploring Various Treatment Types with Neurovalens

17:29 Patient Experience

20:40 Target Nerves and Brain Regions

22:56 Competitors and Differentiators

25:32 What is next for Neurovalens?

27:34 Commercialization

29:55 Patient Education

30:39 Refund if it doesn’t work

31:53 Wellness Device - Big Learnings and Initial Sales

33:40 Early Adopters and Crowdfunding: Indiegogo

35:44 Real World Data and FDA Guidance

37:17 FDA Involvement in Wellness Space

40:23 FDA Confusion Launching Wellness Sleep Product

43:01 Advice for Breaking into Neurotech: Students/Young Professionals

45:14 The Future of Neurotech (20 years)

47:47 Community/Collaboration/Contact

Recorded: 2/8/2024

Host: Robert Murcko 

Neurovalens: https://neurovalens.com/

Free Neurotech Newsletter: https://neurotechnologynews.beehiiv.com/subscribe

Key Moments

0:00 Introduction

2:22 Initial Interest in Neuroscience/Neurotech

4:17 Background and Origins of Synaptrix

6:15 Development of Neuralis Product

7:10 Benefits of Building a Product “In-House”

8:54 In-House Lab Build Out

10:41 Moving Quickly Through Regulatory Stages

11:40 Guardrails Helping Keep Safety and Efficacy Paramount

13:34 Saffron 1 Model

17:01 Saffron 2 and 3 in Development

18:08 Generalizability (“Fluid Matrices that Respond in Real Time to Brain Data)

18:50 Why More Bandwidth is Useful

19:50 Future Path: A Non-Invasive Option for Non-Binary Motor Imagery

20:47 Clinical Study: Empower Study

23:41 Raising Venture Capital

24:48 VC vs Grants: Difference in Requirements

26:26 What is next for Synaptrix?

28:09 Form Factor

29:33 Breaking Into Neurotech

32:26 Breaking Into Neurotech From An Alternate Route

33:54 Predictions for Neurotechnology

36:37 Conclusion and Contact Information

Aryan Govil LinkedIn: https://www.linkedin.com/in/aryangovil/

Synaptrix Labs: https://www.synaptrix-labs.com/

Host: Robert Murcko

Recorded: January 18, 2024

Please note this episode was recorded when Dr. Krinke was still in his former position as of CEO at Newronika.

Key Moments

0:00 Introduction

5:01 Initial Interest in Neuroscience

7:04 Newronika: Background and Origins

9:11 Closed Loop Deep Brain Stimulation Methodology

12:39 Does Closed Loop DBS Pose Additional Risks?

15:20 Newronika WebBioBank

17:07 Data Science/AI: Detecting Waking Up & Freezing of Gait Directly Through the Brain

20:47 What’s Next for Newronika

22:39 Clinical Trial Framework

23:41 Advice: How to Get Involved in Neurotech

27:09 The Future of Neurotech

31:54 Conclusion: Investing, Collaborators, Europe Launch

Host: Robert Murcko

Recorded: January 25, 2024

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Newronika: https://newronika.com/

Lothar Krinke LinkedIn: https://www.linkedin.com/in/lothar-krinke-81955817/

Key Moments

0:00 Introduction

6:25 Master of Surgery Degree

7:57 Initial Interest in Neuroscience/Neurotechnology

9:37 Bionic Vision Technologies 

13:56 BVT Clinical Trials

16:27 BVT Compared to Other Visual Prosthetics and Solutions

21:12 Patient Experiences: Regaining Vision and Confidence

23:11 Ties Between Cochlear and BVT

26:23 What’s Next for BVT?

28:37 Neurotech CEO: Day-to-Day Picture

30:16 How to Get Involved in Neurotech

32:57 The Future of Neurotech

34:07 Conclusion and Contact Info

Host: Robert Murcko

Recorded: January 16, 2024

Free Neurotech Newsletter: https://neurotechnologynews.beehiiv.com/subscribe

Key Moments

0:00 Lee Sidebottom Introduction: Director of Concept Applications at NeuroTracker

5:29 Initial Interest in Neuroscience

12:14 Brain Imaging Technologies Utilized: Currently qEEG. fMRI in Future?

14:55 Early Technology Transfer and Living with CEO

19:52 What is NeuroTracker Working On? Closed-Loop EEG, AR/VR

23:43 NeuroTuner - Exclusive Details - Never Publicly Mentioned Before

32:37 Study with US Air Force: Pilot Training Next

34:28 Learning Curves of Various Populations

37:05 Study with Stock Market Traders

37:53 Longitudinal Study NFL/NHL Combines

39:05 Study with Special Forces

40:10 Studies with French Rugby Team: Blood-Based Biomarkers & Fatigue

42:31 Studies in E-Sports

44:50 Is NeuroTracker Customized for Different Uses and Domains?

50:32 Predictions for Neurotechnology Over Next 20 Years

55:18 Conclusion and Contact Info

Host: Robert Murcko

Recorded: January 12, 2024

Free Neurotech Newsletter: https://neurotechnologynews.beehiiv.com/subscribe

Neurotracker: https://www.neurotrackerx.com/

Lee Sidebottom LinkedIn: https://www.linkedin.com/in/lee-neurotracker/

Dr. Faubert’s Google Scholar: https://scholar.google.ca/citations?user=PDodkWEAAAAJ&hl=fr

3D-Multiple Object Tracking training task improves passing decision-making accuracy in soccer players (Paper): https://www.sciencedirect.com/science/article/pii/S1469029215000631

Critical Review of NeuroTracker (Paper): https://pubmed.ncbi.nlm.nih.gov/33821464/

Ridge Biosignals: https://ridgebiosignals.beehiiv.com/subscribe

Nao Yukawa is a founder of the startup DeMind. Their main product is an app called Lifestack which helps you “Schedule Your Day with Energy in Mind” by using physiological data from your wearables and contextual data from your calendar and other sources.  Nao and his cofounders at DeMind have had an exciting journey so far - they pivoted away from their original idea, are finding some solid traction with this one, raised an investment round to help super charge their growth, and even pitched to legendary angel investor Jason Calacanis.  Regarding whats next: in the future, Lifestack may support neural signal data as one of the app’s inputs.  They are also looking to further expand the contextual data they utilize for a more seamless and intuitive experience.  Those interested in the neurotech and wearable startup scene should keep an eye on Nao and his team.  Recorded: July 25, 2024. Host: Robert Murcko

Key Moments

0:00 Introduction

2:41 Initial Interest in Wearables and Neurotechnology

4:32 Pitching to Jason Calacanis and Founder University

7:02 Juggling Attending Two Universities at Once

8:42 Founding Story Behind DeMind

10:37 Previous Projects and Pivot to Lifestack

13:09 Future Directions: Incorporating Neural Signals into Lifestack

15:33 Lifestack Competitors

16:08 Integrating with Existing Calendar Apps

17:35 Long-Term Goals: Combining Physiological and Contextual Data

19:37 Advice for Getting Involved with Wearables and Neurotech

21:05 Predictions: The Future of Neurotechnology and Wearables

22:17 Book Recommendation: “The Mom Test” and Neuroscience Textbooks

24:42 Where to Find the Lifestack App

25:28 Conclusion and Contact Information

Links

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Lifestack App: https://lifestack.ai/download

Lifestack on Product Hunt: https://www.producthunt.com/products/lifestack

Nao Yukawa LinkedIn: https://www.linkedin.com/in/naoyukawa/

Nao Yukawa Twitter: https://x.com/nyneurotech

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Dr. Iris Brunner (PT, PhD) is an Associate Professor and Researcher at the University of Aarhus’ Hammel Neurocenter in Denmark.  She works in the domain of physiotherapy and neuro-rehabilitation. She is both a researcher and a clinician. Her areas of interest include upper limb motor recovery after stroke, technology-assisted rehabilitation, and life after stroke. Current projects include brain-computer interface training for patients, digital monitoring, and high intensity gait training. She also has a deep interest in clinical translation of research.  Our conversation mainly centers on the use of technology in neuro-rehab and stroke recovery. We also discuss what the future of neuro-rehab may look like and what aspects of various tools and technology are most useful for patients and clinicians. Recorded: March 14, 2024. Host: Robert Murcko

Key Moments: 

0:00 Introduction

1:38 Initial Interest in NeuroRehabilitation

3:20 What is NeuroRehabilitation?

6:22 Examples of Tech Applied to NeuroRehab

9:38 Spatial Neglect

12:01 Precision NeuroRehabilitation

17:23 Current State of Technology in NeuroRehab

19:50 Co-Design: Scaling Up Technology in NeuroRehab

24:00 BCI Research for Upper Limb Paresis After Stroke

28:15 Not There Yet with BCI: Future Directions

29:13 Regulators & Payment

30:40 Predictions for Applications of Technology to Clinical NeuroRehab

34:00 Focus on the End Users

34:50 Conclusion and Contact Info

Links:

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Dr. Brunner's LinkedIn: https://www.linkedin.com/in/iris-brunner-83b91b73/

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