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In this episode, I'm  joined by Dr. Chris Martin-Gill to discuss the critical evaluation of the correlation between end-tidal CO2 and partial pressure of CO2 (PCO2) in acutely ill patients. The episode covers the importance of end-tidal CO2 in the prehospital setting, primarily for verifying airway placement and assessing ventilation adequacy. Dr. Martin-Gill discusses a significant study that he co-authored that analyzed data from over 6,400 patients, finding large discrepancies between end-tidal CO2 and PCO2, particularly in critically ill patients. The discussion highlights the implications of these findings on EMS protocols and the importance of considering patient subpopulations. The episode concludes with recommendations for EMS agencies on how to use end-tidal CO2 readings effectively and the need for further research.

Paper reference: 

PMID: 39546437 DOI: 10.1080/10903127.2024.2430394