Epstein–Barr virus (EBV) has become one of the most intensely studied topics in multiple sclerosis research. But how strong is the evidence linking EBV to MS, and could targeting the virus change the future of treatment and prevention?

In this episode of the ECTRIMS Podcast, host Brett Drummond speaks with Prof. Gavin Giovannoni and Prof. Tomas Olsson about the evolving science connecting infections, immunity and multiple sclerosis.

Together, they explore:

• Molecular mimicry and how EBV proteins may trigger autoimmune responses
• Whether EBV contributes to chronic CNS inflammation and disease progression
• Emerging therapeutic approaches including antivirals, CAR-T cells, and vaccines

This conversation examines one of the most important scientific questions in MS research and the therapeutic possibilities that may emerge from it.