My contribution to the Plenary Session on The Revival of Political Economy will include a discussion of the main core general principles that I have been elaborating on in various forums and journals for the past 5-10 years. Soon this work will emerge as a book, Principles of Political Economy—Applied to Contemporary World Problems. The main principles discussed here will include (a) historical specificity, (b) heterogeneous agents and groups, (c) circular and cumulative causation, (d) contradiction, (e) risk and uncertainty, and (f) uneven development. (There are other principles but these are discussed elsewhere.) These principles are used as core concepts and methodological tools with which to embed political economy problems and policies into the historical juncture, generating a social perspective of the role of human beings and other species, but including geography, in a holistic science of provisioning through protecting and regenerating community assets for present and future generations. Examples of how these principles may be used to example specific problems such as financial crises, climate change, etc, are given throughout the session.