With today's guests, Koen Vree Egberts and Desiree van Noord, we dive into this open-access paper. The study revealed that a stenosis exceeding 50% in the superior mesenteric (SMA) or inferior mesenteric artery on pre-operative computed tomography (CT) scan correlates with an elevated risk of anastomotic leakage (AL) after colorectal surgery. These findings suggest the potential for more personalised risk assessment regarding AL in patients undergoing a colorectal resection by pre-operative screening for mesenteric artery stenosis by duplex ultrasound or CT scan. For cases of SMA stenosis, alternative surgical approaches such as primary stoma creation or (endovascular) revascularisation of the stenosis before colorectal resection could be considered, as well as close post-operative surveillance of patients at risk.