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🔬🫀 When Troponin Lies: A Case of Macrotroponin 🧪❗
We've all seen elevated troponins trigger cath lab calls—but what if the numbers don't add up? This fascinating case from EHJ Case Reports reveals how an IgG–troponin T complex (macrotroponin) mimicked an acute coronary syndrome in a patient with a structurally normal heart and clean coronaries.
📈 Persistently high cTnT
🧪 Normal cTnI
🧫 Confirmed macrotroponin via SDS-PAGE + immunoblotting
🤝 Biochemistry + Clinical Team = Diagnostic Clarity
This is your reminder: always match the lab to the patient, not the other way around.
🎧 Catch our new podcast episode: "Troponin Trickery: When the Lab Lies, Not the Heart"
#Cardiology #LabMedicine #Troponin #Macrotroponin #Diagnostics #ClinicalPearls #CardiacBiomarkers #Podcast #MedEd #EHJCaseReports
By Dr RR Baliga, MD, MBA5
66 ratings
🔬🫀 When Troponin Lies: A Case of Macrotroponin 🧪❗
We've all seen elevated troponins trigger cath lab calls—but what if the numbers don't add up? This fascinating case from EHJ Case Reports reveals how an IgG–troponin T complex (macrotroponin) mimicked an acute coronary syndrome in a patient with a structurally normal heart and clean coronaries.
📈 Persistently high cTnT
🧪 Normal cTnI
🧫 Confirmed macrotroponin via SDS-PAGE + immunoblotting
🤝 Biochemistry + Clinical Team = Diagnostic Clarity
This is your reminder: always match the lab to the patient, not the other way around.
🎧 Catch our new podcast episode: "Troponin Trickery: When the Lab Lies, Not the Heart"
#Cardiology #LabMedicine #Troponin #Macrotroponin #Diagnostics #ClinicalPearls #CardiacBiomarkers #Podcast #MedEd #EHJCaseReports

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