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In this episode, host Catherine Glass speaks with David Cosio about the complex and often overlooked relationship between anxiety and chronic pain. They explore the neurobiological underpinnings of both conditions, how they influence each other, and what the future of integrated pain management may look like, from AI to psychedelics and beyond.
In this episode of Onc Now, host Jonathan Sackier is joined by Simon Lord, Associate Professor in Experimental Cancer Therapeutics, University of Oxford, UK, to discuss translating scientific breakthroughs into real-world treatments. With deep expertise in precision medicine and a passion for innovation in oncology, Lord brings a unique perspective on how the future of cancer therapy is being shaped today.
Timestamps 01:04 – Quickfire question
11:26 – Metabolic imaging
15:26 – Insulin resistance
18:04 – Patient-specific biology
20:35 – Tamoxifen risks
21:57 – Metabolic interventions
24:46 – Lifestyle changes
27:04 – Clinical trials
00:00 – Wishes for healthcare
This podcast has been funded by medac GmbH.
Disclaimer: The views and opinions expressed in this podcast are those of the individual speakers and do not necessarily reflect those of medac GmbH or EMJ. The speakers did not receive honoraria for the recording of this podcast.
In this series, host Catherine Glass speaks with David Cosio about the complex and often overlooked relationship between anxiety and chronic pain. They explore the neurobiological underpinnings of both conditions, how they influence each other, and what the future of integrated pain management may look like, from AI to psychedelics and beyond.
Timestamps:
1:07 - Background
2:10 - Day to Day
3:21 - Why Pain Management
6:06 - Conversations About Pain
7:54 - Key Neurobiological Mechanisms
9:50 - Genetics
11:02 - Brain Mechanisms
11:32 - Biomarkers
In this series, host Catherine Glass speaks with David Cosio about the complex and often overlooked relationship between anxiety and chronic pain. They explore the neurobiological underpinnings of both conditions, how they influence each other, and what the future of integrated pain management may look like, from AI to psychedelics and beyond.
In the second episode of our Rare Lung Diseases podcast mini-series, host Saranya Ravindran delves into the complexities of pulmonary arterial hypertension (PAH) with Neal Chaisson, Assistant Professor of Medicine at the Cleveland Clinic. Chaisson shares insights into why PAH remains under-recognised, the nuances of detection and diagnosis, and what the latest advancements mean for patients and clinicians. The discussion covers everything from early warning signs to future directions in PAH management and research.
Timestamps:
01:05 – Diagnostic workflows
03:58 – Non-invasive tools
05:37 – Right heart catheterisation values
09:05 – Vasoreactivity testing
11:10 – Genetic testing
13:08 – Innovative diagnostics
In the second episode of our Rare Lung Diseases podcast mini-series, host Saranya Ravindran delves into the complexities of pulmonary arterial hypertension (PAH) with Neal Chaisson, Assistant Professor of Medicine at the Cleveland Clinic. Chaisson shares insights into why PAH remains under-recognised, the nuances of detection and diagnosis, and what the latest advancements mean for patients and clinicians. The discussion covers everything from early warning signs to future directions in PAH management and research.
Tinestamps:
00:45 – PAH management
03:05 – Hypoxia
06:42 – Decompensated PAH
10:06 – At-home treatments
12:44 – Multidisciplinary teams
14:50 – Novel therapies
In this episode of Onc Now, host Jonathan Sackier is joined by Stephen Freedland, Surgical Oncologist at Cedars-Sinai Medical Center, Los Angeles, California, USA, to discuss the intersections of biology, behaviour, and bias in prostate cancer. From diet and exercise to disparities in outcomes and promising data on enzalutamide, Freedland challenges assumptions and advocates for a more holistic, equitable approach to care.
Timestamps
01:20 – Background and clinical journey 02:39 – Cancer myths: what needs busting 03:22 – Lifestyle's role in prostate cancer 05:18 – One habit all cancer patients should adopt 06:39 – Yes or No round 10:30 – Diet, obesity, and exercise: the data 13:25 – Mediterranean diet and outcomes 15:30 – Predictive lifestyle factors 16:19 – Racial disparities and root causes 18:35 – Gender-affirming treatment and prostate cancer in trans women 23:20 – Enzalutamide: latest data and developments 25:51 – Broader therapeutic landscape 28:40 – Risk of recurrence 30:19 – Advice for young oncologists 34:00 – Three wishes for the future of prostate cancer care
In the second episode of our Rare Lung Diseases podcast mini-series, host Saranya Ravindran delves into the complexities of pulmonary arterial hypertension (PAH) with Neal Chaisson, Assistant Professor of Medicine at the Cleveland Clinic. Chaisson shares insights into why PAH remains under-recognised, the nuances of detection and diagnosis, and what the latest advancements mean for patients and clinicians. The discussion covers everything from early warning signs to future directions in PAH management and research.
Timestamps:
Part 1:
01:00 – What is PAH
02:34 – Risk factors
04:21 – Misdiagnoses
07:13 – Pathophysiology
10:44 – World Symposium classification
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