EMJ Podcast: Insights For Healthcare Professionals

This podcast was supported by Viatris.

The views and opinions expressed in this podcast are those of the individual speakers and do not necessarily reflect those of Viatris or EMJ. Speakers have received honoraria for their participation.

Explore the challenges and solutions for managing opioid-induced constipation (OIC) in this insightful podcast, featuring discussions from a leading gastroenterologist and an expert pain specialist.

Topics covered include:

• Defining OIC prevalence, underlying mechanisms, and impact on patient wellbeing
• The risks and limitations of laxative use in managing OIC
• The role of peripherally acting mu-opioid receptor antagonists
• Strategies for improved communication and monitoring

This week, Jonathan is joined by Fredrik Schjesvold, Head of the Oslo Myeloma Center Oslo University Hospital, Head of the Norwegian myeloma association, and President of the Nordic Myeloma Study Group.

Timestamps:

(00:00)-Introduction

(04:24)-Research into melflufen

(07:14)- Ide-cel CAR T-cell therapy

(09:40)-Predictors of overall survival

(12:15)-Innovative therapies for refractory myeloma

(14:04)-Bi-specific antibodies

(16:42)-Global guidelines for myeloma

(22:00)-Healthcare economics

(25:45)-Antibody-based therapies

(29:38)- Latest research into amyloidosis

(34:23)-Recent breakthroughs in myeloma

(38:06)-Fredrik's three wishes for healthcare

The publication of this content was funded by Beiersdorf.*

Tune into this Article Recap

Join leading dermatologists and epigenetics researchers Frank Lyko, Firas Al-Niaimi, Hassan Galadari, Elke Grönniger, and Julia Gallinger in this insightful audio recap of an article exploring groundbreaking approaches to facial skin ageing. Highlights from a European Academy of Dermatology & Venereology (EADV) symposium shed light on the latest advancements in epigenetics in combination with innovative skincare interventions.

The discussion covers:

• mechanisms of reversible DNA methylation changes in skin ageing and their potential for transformative treatments;
• the skin-specific age clock, an AI-powered tool which measures biological skin age and supports the creation of Epicelline®, an active ingredient targeting DNA methylation to reverse clinical signs of ageing;
• outcomes in laser therapies with additional use of Epicelline®; and
• case studies on combining Epicelline® with aesthetic treatments such as chemical peels, microneedling, and injectables.

*The following recording is an audio article sponsored and provided by Beiersdorf, and hosted on the EMJ Podcast: Insights for Healthcare Professionals. It is aimed at healthcare professionals and recaps the symposium review article entitled, 'Reverse the Age Clock: Reverse Clinical Signs of Ageing with Epigenetic Skin Science', published in EMJ Dermatology 12.1 in November 2024. To access the full article, visit emjreviews.com. The content included is promotional and contains product placement, highlighting specific products or services, including paid partnerships or sponsorships. Please consult reliable resources or professional advice for any questions about the topics discussed. The opinions expressed do not necessarily represent the opinions of EMJ.

In this episode of the EMJ Podcast, host Jonathan Sackier welcomes Douglas Drossman, a pioneer in disorders of gut–brain interaction. They explore his journey from gastroenterology to psychiatry, the impact of the Rome Foundation, and how neuromodulators are transforming GI treatment.

This is part one of a two-part discussion, don't miss part two!

Timestamps:

• (00:00) – Introduction
• (06:01) – From Rock 'n' Roll to Medicine: Drossman's Musical Past
• (07:48) – The Journey from Gastroenterology to Psychiatry
• (11:35) – Breaking Barriers in Disorders of Gut–Brain Interaction
• (14:14) – The Global Impact of the Rome Foundation
• (17:34) – Neuromodulators: A Game Changer in Treating Painful Gastrointestinal Disorders
• (22:32) – Why Physician Communication Matters More Than Ever

In this episode of Onc Now, Jonathan is joined by Dr Dave Cescon, a Medical Oncologist and Clinician Scientist at the Princess Margaret Cancer Centre, Toronto, Canada. Together, they explore the transformative impact of CDK4/6 inhibitors, challenges in liquid biopsy research, and the potential of mRNA vaccines in oncology.

Timestamps:

(02:44) -Swimming in Toronto: Competitive vs. Open Water

(08:06) -From Internal Medicine to Breast Cancer Research

(14:09) -Translational research and circulating tumour DNA

(19:53) -The role of CDK4/6 inhibitors in breast cancer

(29:04) -FDA approval of ribociclib for high-risk early breast cancer

(31:45) -The future of mRNA vaccines for personalised cancer care

(37:34) -Dave's research challenges and innovations

(39:13) -Three wishes for healthcare

This medical and educational podcast was supported by Edwards Lifesciences and is intended for healthcare professionals.

In this final episode, we learn about how Interventional Cardiologist can play a key role in improving the referral pathway of TAVI patients

Moderator

Jonathan Sackier - EMJ

Speakers: Derk Frank – Interventional Cardiologist, Professor of internal medicine, critical care, and cardiology and Director of the Department for Internal Medicine III (Cardiology, Angiology and Intensive Care Medicine,) at the University Hospital Schleswig-Holstein in Kiel, Germany and the German Centre for Cardiovascular Research Sagar Doshi – Consultant Interventional Cardiologist and Director of the Transcatheter Aortic Valve Implantation (TAVI) programme at the Queen Elizabeth Hospital Birmingham. and Professor of Cardiology Honorary Associate Clinical Professor at the University of Birmingham, and an Honorary Professor at University College Birmingham, in the UK.

In this episode, Jonathan Sackier sits down with Jane van Dis to explore the evolution of obstetrics and gynecology, the fight for gender equity in medicine, and the transformative impact of digital health and FemTech on women's healthcare. They also discuss sustainability in medicine, and her vision for the future of equity, safety, and innovation in women's health.

Timestamps:

(00:00)-Introduction

(01:36)-The evolution of obstetrics

(04:24)-Inequities and biases

(07:03)-Patient safety

(09:37)-Racial disparities in the USA

(11:26)-Environmental exposure

(15:50)-Equity in healthcare

(18:18)-Digital innovation in women's health

(22:01)-Advancements in FemTech

(27:16)-Sustainability in healthcare

(32:13)-The future of women's health

This week, Jonathan is joined by Anna Sureda, Head of the Clinical Hematology Department at Institut Català d'Oncologia - Hospital Duran i Reynals, Barcelona, Spain, and President of the European Society for Blood and Marrow Transplantation (EBMT) Association, to discuss the latest in lymphoma therapies and stem cell transplantation.

Timestamps:

(00:00)-Introduction

(01:48)-Memorable travels

(07:44)-Sureda's journey into hematology

(12:40)-Breakthroughs in lymphoma treatment

(17:54)-Advances in stem cell transplantation

(20:26)-EBMT initiatives

(29:17)-Allogeneic transplantation for T cell lymphomas

(34:32)-Challenges in treatment accessibility

(41:35)-How can we ensure health equity?

(46:00)-Advice to young hematologists

(47:40)-Sureda's three wishes for healthcare

This podcast has been supported by CSL Behring.

Bronchiectasis is a multifaceted condition with unique diagnostic and treatment considerations, presenting significant challenges for healthcare professionals. Join leading respiratory experts as they discuss bronchiectasis and the latest insights on managing inflammation in rare lung diseases.

Topics covered include:

• Advances in the epidemiology of bronchiectasis and its prevalence in chronic obstructive pulmonary disease and alpha 1 antitrypsin deficiency
• Recognising symptoms and identifying risk factors for recurrent exacerbations
• Diagnostic approaches, including the use of CT scans and laboratory tests
• Evidence-based treatment strategies and measures to prevent exacerbations

This week, Jonathan Sackier is joined by Janet Abrahm, Professor of Medicine at Harvard Medical School and Institute Physician at Dana-Farber Cancer Institute, to break stigmas around palliative care and explore the evolution of supportive oncology.

Timestamps:

(00:00)-Introduction

(03:55)-Abrahm's journey into palliative care

(09:10)-A perspective on cannabinoids

(12:21)-The evolution of palliative oncology

(16:39)-Breaking stigma around palliative care

(20:20)- Differences in global approaches to palliative care

(25:43)-Medical aid in dying

(35:08)-Advice to young doctors

(37:03)-Abrahm's three wishes for healthcare