EMJ Podcast: Insights For Healthcare Professionals

Salvatore Brugaletta joins host Catherine Glass to explore how intracoronary imaging has transformed modern percutaneous coronary intervention (PCI). From intravascular ultrasound and optical CT to stent optimisation, vascular dysfunction, and AI-enhanced image interpretation, this episode examines the technologies improving procedural precision and patient outcomes.

Timestamps:

0:55 – IVUS and OCT

2:58 – Endothelial recovery

4:55 – Stent failure mechanisms

6:19 – Barriers to adoption

8:18 – Innovations in imaging

In this rapid-fire episode, Salvatore Brugaletta answers key questions on interventional cardiology, coronary imaging, bioresorbable scaffolds, vascular healing, and the future of percutaneous coronary intervention. From AI-assisted procedures to device innovation and career advice, this concise episode offers expert insight into the evolving world of coronary intervention.

In this episode of Onc Now, Mary Disis, Director of the University of Washington's Medicine Cancer Vaccine Institute, Seattle, USA, explores the science and future of cancer vaccines. She discusses how vaccines fit into today's immunotherapy landscape, the evolution of human epidermal growth factor receptor 2 (HER2)-targeted therapies, progress in breast cancer vaccines, the promise of cancer prevention, and the key priorities for survivorship and future oncology care.

Timestamps:

00:00 – Introduction

01:28 – Cancer Vaccines Explained

03:57 – Journey Into Cancer Immunology

06:38 – Cancer Vaccines in Immunotherapy

10:02 – Leading the Cancer Vaccine Institute

13:26 – Progress in Breast Cancer Vaccines

18:39 – HER2 Research and Treatment Evolution

21:30 – Future of Preventive Cancer Vaccines

26:39 – Priorities for Cancer Survivorship

30:30 – Three Wishes for Oncology's Future

How does scientific evidence become public policy? In the final episode, Christopher Cogle discusses the challenges of translating healthcare innovation into large-scale policy change. Topics include housing policy and mortality, youth tobacco use, vaping regulation, and how the COVID-19 pandemic reshaped public health decision-making.

Timestamps:

00:49 – Public Startup

07:08 - Challenges

15:01 – Housing policy

16:28 – Tobacco policy

19:05 – COVID-19

In Part 2, Christopher Cogle examines the long-term realities facing cancer survivors. From vaccine hesitancy and quality-of-life disparities to healthcare access and survivorship policy, this episode explores how systems can better support patients beyond active treatment.

Timestamps:

00:50 – Vaccine hesitancy

04:33 – QoL after cancer

07:30 – Policy support

11:10 – Survivorship care

In this episode of Hema Now, John Maher reflects on more than 2 decades at the forefront of CAR-T cell research. He discusses the major milestones that have transformed CAR-T therapy into a clinical reality, the biological barriers that continue to limit success in solid tumours, and the next-generation engineering approaches being developed to enhance efficacy and safety. Maher also shares insights into the origins of the CAR Mechanics Group, the challenge of overcoming the tumour microenvironment, and his vision for the future of cellular immunotherapy.

Timestamps:

00:00 – Introduction

01:07 – Career Journey into Immunotherapy

02:22 – Key CAR-T Therapy Milestones

05:50 – Overcoming Solid Tumour Barriers

09:14 – Origins of CAR Mechanics

12:35 – Most Exciting Current Innovations

16:08 – Improving CAR-T Safety Profiles

20:07 – Challenges of Tumour Microenvironments

23:04 – Future of Cellular Immunotherapy

27:15 – Three Magic Wishes

In this first deep dive, Christopher Cogle explores the evolving landscape of acute myeloid leukaemia (AML). He discusses the challenge of translating research into real-world outcomes, emerging immunotherapies, precision diagnostics, and how innovations such as the Acute Leukemia Methylome Atlas may reshape AML management in the future.

Timestamps:

00:55 – Research Gaps

03:50 – Biologics

05:46 – AML Atlas

09:15 – Immunotherapy

Christopher Cogle joins the EMJ Podcast for a quickfire discussion on oncology, innovation, and public health policy. From personalised cancer care and AI in medicine to AML challenges and healthcare reform, he shares concise insights from across clinical medicine and policy leadership.

In the final episode, Sharonne N. Hayes discusses how structural inequities and unconscious bias continue to affect cardiovascular outcomes for women and minority patients. From improving diversity in research to leveraging social media responsibly, this episode explores what the future of equitable cardiovascular care could look like.

Timestamps:

0:58 – Health equity

4:02 – Improving representation

7:10 – Role of social media

9:54 – 10-year prediction

11:08 – Sharonne's wish

In Part 2, Sharonne N. Hayes explores spontaneous coronary artery dissection (SCAD) and how it challenges traditional assumptions about heart attacks. Learn how SCAD differs from atherosclerotic disease, what recent research has uncovered, and how clinicians can navigate complex management decisions.

Timestamps:

1:06 – What is SCAD?

2:47 – Practice-changing insights

6:35 – Hormonal influences

8:20 – Therapeutic ambiguity