ENT Update

ENT Update

By 洪士涵醫師ScienceHealth & Fitness
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ENT Update episodes

  • Episode 50 | 2026/05/26
    ENT Update Podcast EP53 - Otology and Audiology (2026/05/26)
    Papers discussed:
    1. vHIT and cVEMPs in sudden SNHL - Rodriguez-Izquierdo et al. Acta Otolaryngol 2026 - DOI:10.1080/00016489.2026.2671348
    2. Motorized vs manual CI insertion - Hear Res 2026 - DOI:10.1016/j.heares.2026.109653
    3. Pseudoprogression in Koos grade 4 VS after SRS - Schouten et al. J Neurooncol 2026 - DOI:10.1007/s11060-026-05619-y
    4. Facial palsy impact on VS QoL - van Vollenhoven et al. Otolaryngol Head Neck Surg 2026 - DOI:10.1002/ohn.70255
    9 min
  • Episode 49 | 2026/05/25
    ENT Update Podcast EP52 - 頭頸外科與腫瘤學（2026/05/25）
    本集論文：
    1⃣️ Near-infrared fluorescence imaging-guided surgery using cRGD-ZW800 to improve surgical resection margins in oral cancer: a phase I/II feasibility trial
    PMID: 42173866 https://pubmed.ncbi.nlm.nih.gov/42173866/
    DOI: 10.1038/s41467-026-73554-7
    關鍵發現：Phase I/II trial (n=24) 顯示 cRGD-ZW800 螢光導引可即時改變口腔癌手術邊緣決策，四例病人中偵測到肉眼無法辨識的腫瘤殘留
    2⃣️ De-Escalated Adjuvant Radiation Therapy in Patients With HPV-Positive Oropharyngeal Cancer
    PMID: 42149594 https://pubmed.ncbi.nlm.nih.gov/42149594/
    DOI: 10.1001/jamanetworkopen.2026.12837
    關鍵發現：NCDB 資料庫 3300+ 病人，降階放療組兩年局部控制率 93%，急性三度黏膜炎從 42% 降至 18%
    3⃣️ Dissociating recurrence risk from mortality: a 10 year analysis challenging the independent prognostic value of depth of invasion in oral cavity squamous cell carcinoma
    PMID: 42107224 https://pubmed.ncbi.nlm.nih.gov/42107224/
    DOI: 10.1016/j.oraloncology.2026.108001
    關鍵發現：多變項分析中 DOI 獨立預後價值大幅衰減（HR 2.1→1.3），不應單獨用於治療決策
    4⃣️ Transoral Robotic Surgery-Based Treatment Versus Definitive Chemoradiation for Oropharyngeal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis
    PMID: 42087273 https://pubmed.ncbi.nlm.nih.gov/42087273/
    DOI: 10.1002/hed.70308
    關鍵發現：TORS 組五年存活率 88% vs 放化療 85%（無顯著差異），但吞嚥功能與口乾發生率顯著較優
    5⃣️ The submental artery pedicled flap for peri-auricular and parotid reconstruction: a comparative cohort
    PMID: 42176358 https://pubmed.ncbi.nlm.nih.gov/42176358/
    DOI: 10.1016/j.oraloncology.2026.108032
    關鍵發現：頦下動脈皮瓣 vs 顳肌皮瓣，美觀滿意度更高、手術時間縮短 40 分鐘、住院天數更短，皮瓣存活率 100%
    6⃣️ Osteoradionecrosis After Modern Radiotherapy for Oral Cavity Cancer: Incidence and Risk Factors
    PMID: 42111429 https://pubmed.ncbi.nlm.nih.gov/42111429/
    DOI: 10.1002/lio2.70431
    關鍵發現：IMRT/VMAT 時代五年 ORN 累積發生率 7.2%，重度 ORN 2.8%；關鍵風險因子：下齒齦原發腫瘤、V6025%、放療前拔牙
    15 min
  • Episode 48-Special | 2026/05/25
    Episode 51-Special | 2026/05/25 — 頭頸部腫瘤最新研究特輯
    主持人：傅醫師（Puck）& 林醫師（Kore）
    本集論文：
    1. 單細胞 HNSCC 惡性細胞異質性與 MCScore 預測工具 (IUBMB Life)
    DOI: https://pubmed.ncbi.nlm.nih.gov/42068156/
    2. STING 表現預測 LA HNSCC 治療失敗型態 (JNCI Cancer Spectrum)
    DOI: https://pubmed.ncbi.nlm.nih.gov/41569294/
    3. HYDRA/HYPNO 低分割放療試驗
    DOI (HYDRA): https://pubmed.ncbi.nlm.nih.gov/42000366/
    DOI (HYPNO): https://pubmed.ncbi.nlm.nih.gov/41711624/
    4. ctDNA MRD 監測：MERIDIAN Phase II + PECAN Trial (AACR 2026)
    5. 放療中斷對預後影響 + SBRT 新技術 (JAMA Otolaryngology)
    DOI: https://pmc.ncbi.nlm.nih.gov/articles/PMC12679426/
    6. Rilvegostomig (TIGIT/PD-1) + MICVO ADC (AACR 2026)
    7. HPV+ OPSCC 去強度策略與生物標記
    DOI: https://onlinelibrary.wiley.com/doi/10.1002/cnr2.70539
    18 min
  • Episode 46-Special | 2026/05/23
    ENT Update Podcast 特輯 - 2026/05/23 睡眠外科最新進展
    主持人：傅醫師（Puck）& 林醫師（Leda）
    討論主題：
    1. THN3：pHGNS 三年追蹤結果 — Chest 2026
    2. OSA手術門診心血管健康 — Laryngoscope 2026
    3. HGNS 反應預測 — JAMA Otolaryngol 2026
    4. 形態量測取代DISE — OTO Open 2026
    5. 頭頸癌存活者OSA盛行率83.7%
    6. 睡眠外科與全身健康
    7. GLP-1 RA 與睡眠外科
    修復版：正確outro時間點、無尾音雜音
    7 min
  • Episode 45-Special | 2026/05/23
    ENT Update Podcast 特輯 - 2026/05/23（週六：人工智慧在耳鼻喉科應用）修復版
    主持人：傅醫師（Puck）& 林醫師（Leda）
    討論主題：
    1. ChatGPT-5 vs ENT主治醫師 — Egyptian J Otolaryngol
    2. Emory AI 語音喉癌檢測 — 93%準確率
    3. Flinders Multimodal AI 中耳炎診斷
    4. ML預測頭頸癌ENE — Laryngoscope
    5. AI Chasm分析 — Nature npj Digital Medicine
    6. Lightweight DL鼻息肉分類 — Edge computing
    7. Stanford 睡眠AI穿戴裝置
    修復：修正outro時間點、消除尾音雜音
    8 min

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Ear, nose and throat head and neck medicine latest information. Weekly curated international literature, research progress and clinical updates for medical professionals. Content includes: otology,…