This episode isa snippet from the late 2023 Veterinary Pain Management Workshop hosted by IVDI, which offers a deep dive into nerve growth factor inhibitors, focuses on the cutting-edge therapeutic agents, Salencia for cats and Librella for dogs, addressing their mechanism and impact on pain management. Dr. Mark Epstein, a renowned pain management expert, shares insights from a 2023 workshop, breaking down complex mechanisms and their practical applications in clinical settings.

 

Main Talking Points:

• Introduction to Nerve Growth Factor (NGF) and its inhibitors.

• The biology and impact of NGF on pain pathways.

• Clinical use and observations with Silencia in cats and Labrella in dogs.

• Potential concerns and ongoing questions about NGF inhibitors.

• Co-administration with NSAIDs and its implications.

Interesting Quotes:

• "NGF is largely responsible for amplifying neurogenic inflammation, making it a prime target for therapeutic intervention."

• "Silencia and Labrella offer significant improvements in mobility and quality of life for cats and dogs suffering from osteoarthritis."

Timestamps:

• 0:00 - Introduction to the episode

• 1:30 - Speaker introduction: Dr. Mark Epstein

• 2:00 - Overview of nerve growth factor inhibitors

• 4:00 - The science behind NGF and pain management

• 6:00 - Clinical observations with Silencia and Labrella

• 8:00 - Addressing concerns and unanswered questions

• 9:30 - Discussion on co-administration with NSAIDs

 

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This episode sheds light on the pivotal role of nerve growth factor inhibitors in managing chronic pain in pets. Dr. Mark Epstein's expertise offers a comprehensive understanding of how these inhibitors work, their clinical benefits, and the nuanced considerations in their application.