This week on The Genetics Podcast, Patrick is joined by Madhuri Hegde, SVP and Chief Scientific Officer of Revvity. They discuss Revvity’s advances in ultra-rapid clinical-grade sequencing, opportunities, challenges, and global inequities in newborn screening, and the dilemma of resequencing versus long-term data storage.

Show Notes: 

0:00 Intro to The Genetics Podcast

00:59 Welcome to Madhuri

01:52 Rebranding Revvity as a healthcare company

02:51 Advancements in sequencing and Revvity’s projects, including newborn screening tests and clinical ultra-rapid sequencing

12:29 Opportunities and challenges for newborn sequencing and global inequity in access

17:46 Price of sequencing and data storage versus resequencing considerations

21:10 Complexities and nuances of genomic data interpretation

23:28 Rethinking data portability and storage across the lifespan

26:00 Understanding penetrance and population genetics through lifelong sequencing

27:36 Scaling genetic counseling to match advancements and the potential value of chatbots

32:45 The promise of proteomics and translating Olink data to the clinic

34:31 Implementing polygenic risk scores in clinical management  

37:12 Transitioning from academia to industry and insights into product development

38:37 Closing remarks

Find out more

• Revvity (https://www.revvity.com/)

Please consider rating and reviewing us on your chosen podcast listening platform! 

https://drive.google.com/file/d/1Bp2_wVNSzntTs_zuoizU8bX1dvao4jfj/view?usp=share_link