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What is Maxwell's demon, and what is its role in biology? How do molecular demons underpin life? Does life really defy entropy? On this episode of Big Biology, we talk with Paul Davies, a cosmologist at Arizona State University and the Director of the Beyond Center for Fundamental Concepts in Science. His recent book, "The Demon in the Machine," tackles Schrodinger's big question "What is life?," arguing that information is the key that distinguishes living from non-living things. You can learn more about Paul’s book as well as his other work on the role of information in biology via our website: bigbiology.org.