Where do you take your career after you’ve won all of science’s biggest prizes? In this episode of Stereo Chemistry, C&EN executive editor Lisa Jarvis sits down with Nobel laureates Frances Arnold and Jennifer Doudna to hear about whether their career goals changed after they got that early-morning phone call in October and how the pandemic has shifted the way they approach their work. A script of this episode is available at bit.ly/3u7jCW7. Sign up for C&EN's newsletter at cenm.ag/chemnewsletter. Catch up on last year's package of trailblazing women chemists, edited by Jennifer Doudna, at cenm.ag/2020trailblazers. Image credit: Caltech (Arnold)/Laura Morton Photography (Doudna)