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This study examined the effects of an invasive strategy, including coronary angiography and subsequent revascularization, compared to a conservative approach for older adults (≥75 years) experiencing non–ST‐segment–elevation acute coronary syndrome (NSTE‐ACS). The meta-analysis of nine studies indicated that invasive strategies significantly reduced the risk of death or myocardial infarction, myocardial infarction, and subsequent revascularization without increasing the risk of major bleeding. Despite limitations, the results highlight the potential benefits of invasive strategies for older adults with NSTE‐ACS, underscoring the need for future trials to further explore the nuances of geriatric conditions and to better represent the growing older adult population.
By Abdulla A. Damluji, MD, PhD3.8
66 ratings
This study examined the effects of an invasive strategy, including coronary angiography and subsequent revascularization, compared to a conservative approach for older adults (≥75 years) experiencing non–ST‐segment–elevation acute coronary syndrome (NSTE‐ACS). The meta-analysis of nine studies indicated that invasive strategies significantly reduced the risk of death or myocardial infarction, myocardial infarction, and subsequent revascularization without increasing the risk of major bleeding. Despite limitations, the results highlight the potential benefits of invasive strategies for older adults with NSTE‐ACS, underscoring the need for future trials to further explore the nuances of geriatric conditions and to better represent the growing older adult population.

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