Interpreting toxicology results after death isn’t always straightforward—especially when time is a factor. In this episode, we discuss the post-mortem interval (PMI) and how it complicates toxicological interpretation. We explore how decomposition affects drug concentrations and why traditional methods of estimating PMI have limitations. Could omics-based approaches, like metabolomics and proteomics, offer a more accurate way to determine time of death? Tune in as we break down the science behind PMI and its impact on forensic toxicology.

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Links to the paper we discussed: https://pmc.ncbi.nlm.nih.gov/articles/PMC11817326/