Reg Bloor is a guitarist, instrument builder, and founder of the Systems Neutralizers record label. For 18-years she collaborated with composer Glenn Branca, serving as a guitarist, concertmaster, and manager on international tours and multiple albums. On June 12, 2026, she will conduct Branca's Symphony No. 13 at Lincoln Center, and she is currently preparing the release of his Symphony No. 4.

Independently, Reg has released four solo guitar albums, co-founded the bands The Paranoid Critical Revolution and Twitcher, and contributed to several film soundtracks.