In Episode 4 of the Total Knee Success Podcast we explore the powerful role of nutrition in total knee replacement healing. We break down why protein, hydration, anti-inflammatory foods, vitamins, and minerals are essential for tissue repair, scar formation, and steady energy. We also look at how GLP-1 weight loss medications may impact muscle and success, and what steps patients can take to protect strength. Practical advice, red flags to watch for, and clear science-backed takeaways make this episode a must-listen for anyone preparing for or moving forward after knee replacement.

Learn more and access additional resources at TotalKneeSuccess.com.

Medical Disclaimer The Total Knee Success Podcast is for educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your surgeon, nutritionist, dietician, therapist, or other qualified health provider with any questions you may have regarding your specific condition or care. Never disregard professional advice or delay seeking it because of something you heard on this podcast. This podcast is not affiliated with Michelle's clinic or teaching roles.

Amazon Affiliate Disclaimer As an Amazon Associate, I earn from qualifying purchases. This means that if you click on a product link in my show notes or at TotalKneeSuccess.com and make a purchase, I may receive a small commission at no extra cost to you. These commissions help support the podcast and allow me to keep creating free, evidence-based content. I only share products that are commonly recommended for knee replacement and that patients have found helpful.

References

Bohl DD, Volpe KA. Nutritional optimization in total joint arthroplasty: a review of the literature. J Arthroplasty. 2017;32(9):2831-2839. doi:10.1016/j.arth.2017.05.016.

Zhang Z, Xu H, Ma J, et al. Anti-inflammatory dietary patterns and joint health after orthopedic surgery. Clin Nutr. 2020;39(11):3456-3463. doi:10.1016/j.clnu.2020.05.013.

Cross MB, Yi PH, Thomas CF, Garcia J, Della Valle CJ. Evaluation of malnutrition in orthopaedic surgery. J Am Acad Orthop Surg. 2014;22(3):193-199. doi:10.5435/JAAOS-22-03-193.

Miller PE, Van Elswyk M, Alexander DD. Dehydration and orthopedic surgical outcomes: a systematic review. Nutr Clin Pract. 2018;33(1):48-58. doi:10.1002/ncp.10028.

O’Neill SC, Queally JM, Hickey A, et al. Vitamin D status and surgical outcomes following knee arthroplasty. J Arthroplasty. 2017;32(9):3020-3024. doi:10.1016/j.arth.2017.05.002.

Hunger RE, et al. Individualized nutrition care improves strength and independence after knee replacement. Clin Nutr ESPEN. 2020;35:205–211. doi:10.1016/j.clnesp.2019.10.015.

Biolo G, Tipton KD, Klein S, Wolfe RR. An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein. Am J Physiol Endocrinol Metab. 1997;273(1):E122-E129. doi:10.1152/ajpendo.1997.273.1.E122.

Changes in lean body mass with GLP-1-based treatments for obesity. Curr Opin Endocrinol Diabetes Obes. 2024;31(5):223-229. doi:10.1097/MED.0000000000000863.

Zhou Y, Liu T, Zhang Y, et al. Inhibition of GDF8 and activin A protects against GLP-1 RA-induced muscle loss while enhancing fat loss. Nat Commun. 2025;16(1):1552. doi:10.1038/s41467-025-59485-9.

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