IgA nephropathy (IgAN) has a decades-long progression that requires careful monitoring of key biomarkers to optimize management. Hematuria, proteinuria, and estimated glomerular filtration rate levels are all critical to tracking the progression of the disease, and understanding how they’re connected can not only improve prognostication but also guide earlier, more targeted interventions to preserve kidney function. Joining Dr. Gates Colbert to walk through these markers and their importance is Dr. Abdallah Geara. He's an Associate Professor of Clinical Medicine, Clinical Director of the Glomerular Diseases Program, and the Director of Onconephrology at Penn Medicine in Philadelphia.