Having entered the recent public and research zeitgeist, microdosing involves consuming sub-perceptual doses of psychedelic drugs, allegedly to enhance performance, creativity, and wellbeing. The results of research to date have been mixed. Whereas most studies have reported positive impacts of microdosing, some microdosers have also reported adverse effects. In addition, research to date has revealed inconsistent patterns of change in personality traits. This prospective study explored the relationship between microdosing, personality change, and emotional awareness.