Proton pump inhibitors (PPIs) are among the most commonly prescribed class of medication for acid-related disorders. But what are the long-term consequences of PPIs? And how have they changed the prescribing pattern among gastroenterologists? To help us better understand this topic, Dr. David Leiman, Assistant Professor of Medicine at Duke University School of Medicine, joins Dr. Peter Buch to discuss how we should be utilizing PPIs with our patients.