From First Principles

FFP EP. 18 | 3I/ATLAS Explained, Forensic Fingerprints & Alzheimer’s Breakthrough


Listen Later

Hosted by Lester Nare and Krishna Choudhary, this episode spans astrophysics, forensic chemistry, and neuroimmunology. We begin with a deep dive into 3I/ATLAS, only the third confirmed interstellar object to ever pass through our solar system — larger and stranger than ‘Oumuamua and Borisov, with new imagery released as NASA reopened operations. Then we break down a true-crime forensic breakthrough from Maynooth University that reveals how to recover fingerprints from fired bullet casings — a technique that could radically accelerate criminal investigations. And we close with a Max Planck Institute discovery identifying a regulatory microglial state in the brain that may finally clarify why Alzheimer’s develops — and how immune dysfunction, not just plaques, drives the disease.


Summary

  • The third interstellar visitor — 3I/ATLAS joins ‘Oumuamua and Borisov as only the third object ever observed entering the solar system from interstellar space, with new NASA imagery revealing structure, trajectory, and compositional clues.


  • A forensic chemistry breakthrough — researchers at Maynooth University develop a technique to retrieve latent fingerprints from fired shell casings, combining heat-stable organic residues with spectroscopic imaging.


  • A new model of Alzheimer’s — Max Planck Institute scientists uncover a microglial “regulatory” state (a T-reg–like analogue) activated through CD28-dependent pathways, reshaping how the field thinks about plaques, neuroinflammation, and therapeutic targets.


Show Notes

  • 3I/ATLAS — Interstellar Object Updates (NASA / JPL)
  • Forensic Chemistry: Fingerprints on Fired Casings (Maynooth University)
  • Alzheimer’s Microglia Study — Max Planck Institute / Univ. of Cologne
...more
View all episodesView all episodes
Download on the App Store

From First PrinciplesBy Krishna Choudhary and Lester Nare

  • 5
  • 5
  • 5
  • 5
  • 5

5

32 ratings


More shows like From First Principles

View all
Stuff You Should Know by iHeartPodcasts

Stuff You Should Know

78,728 Listeners

Radiolab by WNYC Studios

Radiolab

43,993 Listeners

Wait Wait... Don't Tell Me! by NPR

Wait Wait... Don't Tell Me!

38,831 Listeners

My Brother, My Brother And Me by The McElroys

My Brother, My Brother And Me

30,123 Listeners

Making Sense with Sam Harris by Sam Harris

Making Sense with Sam Harris

26,315 Listeners

Science Vs by Spotify Studios

Science Vs

12,117 Listeners

Science Friday by Science Friday and WNYC Studios

Science Friday

6,439 Listeners

What Trump Can Teach Us About Con Law by Roman Mars

What Trump Can Teach Us About Con Law

3,976 Listeners

Ologies with Alie Ward by Alie Ward

Ologies with Alie Ward

24,508 Listeners

Decoder Ring by Slate Podcasts

Decoder Ring

2,128 Listeners

Throughline by NPR

Throughline

16,376 Listeners

Short Wave by NPR

Short Wave

6,567 Listeners

Unexplainable by Vox

Unexplainable

2,311 Listeners

Serious Trouble by Josh Barro and Ken White

Serious Trouble

433 Listeners

Hasan Minhaj Doesn't Know by 186k Films

Hasan Minhaj Doesn't Know

470 Listeners