Former President Joe Biden has been diagnosed with an aggressive form of prostate cancer that has spread to his bones. The news came Sunday in a statement from his office detailing a Gleason score of 9 — the most severe grade for this cancer. It means it’s fast-moving and deadly serious.

Doctors say it’s hormone-sensitive, which opens the door for treatment. But make no mistake — cancer that reaches the bones is not curable.

The 82-year-old has long championed cancer research, after losing his son Beau to brain cancer in 2015.

In office, he revived the Cancer Moonshot and pushed to cut U.S. cancer deaths in half over the next 25 years. Now, he’s facing the very disease he once vowed to end.

Former Vice President Kamala Harris, President Donald Trump, former President Barack Obama and former Secretary of State Hillary Clinton all offered public well-wishes.

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