S&P 500 future is down (1.7%) and Nasdaq 100 future is down (2%) as of now, both pointing to a sharply lower open today, as geopolitical tensions and tariff concerns continue to mount. Asian equities ended mostly lower on Tuesday with Japan leading the declines. European markets also opened broadly lower with major benchmarks down over 1%.

Companies Mentioned: Viiv Healthcare, Ardelyx, Rapt Therapeutics, Google