Dr. Reisa Sperling is leading a study into a new drug treatment that could prevent memory loss before symptoms show. The changes in the brain that lead to Alzheimer’s occur years before symptoms, such as forgetfulness, appear. Dr. Sperling is leading the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s (A4 for short) study which targets amyloid, a protein that builds up in the brain and that some researchers believe leads to memory loss. One thousand men and women are needed to participate in this three-year study, which has over 60 site locations. This call was made possible by the generous support of the Alzheimer's Drug Discovery Foundation.