COVID-19 vaccinations have begun in the U.S., with a New York City nurse on Monday becoming the first recipient outside of clinical trial participants. But some Americans remain skeptical, in part due to perceived political influence. Dan discusses the process, politics and science of COVID-19 vaccinations with Margaret Hamburg, who led the FDA between 2009 and 2015. 

Plus, Axios Codebook author Zach Dorfman joins to discuss the cybersecurity hack that has impacted both the U.S. Treasury and Commerce departments.