Dr RR Baliga's "Got Knowledge Doc" Podkast

From Mom or Dad? It Makes a Difference whether Growth or Metabolsim πŸ€”πŸ‘©β€πŸΌπŸ‘¨β€πŸΌ


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πŸš€ New in Nature: Groundbreaking study reveals how the origin of your genes β€” from mom πŸ‘©β€πŸΌ or dad πŸ‘¨β€πŸΌ β€” can push human growth πŸ“ and metabolism πŸ”₯ in opposite directions!

🧬 Using data from 236,781 people across UK Biobank, Estonian Biobank, and MoBa, researchers uncovered 30+ parent-of-origin effects (POEs), many showing bipolar impacts β€” boosting traits when inherited from one parent, reducing them from the other.

βš–οΈ Findings support the parental conflict hypothesis: paternal genes tend to promote growth πŸš€, while maternal genes conserve resources πŸ›‘οΈ. These insights were invisible to standard GWAS, proving the power of family-rich biobanks in unlocking hidden genetic layers.

πŸ”— Read the paper: https://doi.org/10.1038/s41586-025-09357-5

#Genomics #GWAS #Biobanks #ParentOfOrigin #Growth #Metabolism #PrecisionMedicine

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Dr RR Baliga's "Got Knowledge Doc" PodkastBy Dr RR Baliga, MD, MBA

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