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Fueling Immunity: When Eating Becomes Therapy 🍽️💊🛡️
A meal may be more than nutrition—it may be immunotherapy. 🍽️⚡
In a striking Nature study, T cells sampled just 6 hours after feeding showed enhanced metabolic fitness, cytokine production, and persistence compared to the fasted state. 🧠🔥
Mechanistically, chylomicron-derived lipids → LDLR → mTORC1 → protein translation, fueling durable immune function.
Even more compelling: postprandial CAR-T cells demonstrated superior cytotoxicity.
Clinical implication? Timing may matter—before vaccines, before cell therapy, before immune engagement. ⏱️
Feed. Fuel. Fight. 🛡️✨
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By Dr RR Baliga, MD, MBA
5
66 ratings
A meal may be more than nutrition—it may be immunotherapy. 🍽️⚡
In a striking Nature study, T cells sampled just 6 hours after feeding showed enhanced metabolic fitness, cytokine production, and persistence compared to the fasted state. 🧠🔥
Mechanistically, chylomicron-derived lipids → LDLR → mTORC1 → protein translation, fueling durable immune function.
Even more compelling: postprandial CAR-T cells demonstrated superior cytotoxicity.
Clinical implication? Timing may matter—before vaccines, before cell therapy, before immune engagement. ⏱️
Feed. Fuel. Fight. 🛡️✨
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