Func Med Nation Podcast

In this episode, I sit down with Dr. Brad Rachman to explore his remarkable journey from a personal autoimmune crisis to decades of work in functional medicine and laboratory medicine, including his time with Genova Diagnostics. We talk about the early days of functional medicine, how the field has evolved, and how clinicians can choose tests that actually matter instead of drowning in data.

Brad shares his origin story with ankylosing spondylitis and how it shaped his entire clinical philosophy. We get into high‑value markers like complement C3/C4, MMP‑9, TGF‑β1, GGT, oxidized LDL, and CD4/CD8 ratios, as well as the role of stealth pathogens such as EBV, Coxsackie, and Chlamydia pneumoniae. We also break down practical approaches to assessing dysglycemia using tools like HOMA and C‑peptide, and how to build a testing strategy that gives clarity instead of overwhelm.

We also dive into clinical models and practice design—everything from volume‑based care versus engagement‑based care, to creating a patient roadmap, to using AI for long‑term 10‑year risk analysis. Brad shares his therapeutic priorities around diet, lifestyle, and pro‑resolving mediators, and we spend time on the philosophy of vitalism: trusting and stewarding the body’s innate ability to self‑regulate.

If you’re a clinician, you’ll walk away with practical insights on which tests are truly actionable, how to communicate with patients during symptom flares, when to prioritize lifestyle over supplements, and how to design care that restores long‑term vitality and resilience.

LINKS
Rachman Clinic

TikTok @dr.brad.rachman
Instagram @rachmanclinic
YouTube @drbradrachman
LinkedIn linkedin.com/company/rachman-clinic

In this episode, I sit down with Dr. Brad Rachman to explore his remarkable journey from a personal autoimmune crisis to decades of work in functional medicine and laboratory medicine, including his time with Genova Diagnostics. We talk about the early days of functional medicine, how the field has evolved, and how clinicians can choose tests that actually matter instead of drowning in data.

Brad shares his origin story with ankylosing spondylitis and how it shaped his entire clinical philosophy. We get into high‑value markers like complement C3/C4, MMP‑9, TGF‑β1, GGT, oxidized LDL, and CD4/CD8 ratios, as well as the role of stealth pathogens such as EBV, Coxsackie, and Chlamydia pneumoniae. We also break down practical approaches to assessing dysglycemia using tools like HOMA and C‑peptide, and how to build a testing strategy that gives clarity instead of overwhelm.

We also dive into clinical models and practice design—everything from volume‑based care versus engagement‑based care, to creating a patient roadmap, to using AI for long‑term 10‑year risk analysis. Brad shares his therapeutic priorities around diet, lifestyle, and pro‑resolving mediators, and we spend time on the philosophy of vitalism: trusting and stewarding the body’s innate ability to self‑regulate.

If you’re a clinician, you’ll walk away with practical insights on which tests are truly actionable, how to communicate with patients during symptom flares, when to prioritize lifestyle over supplements, and how to design care that restores long‑term vitality and resilience.

LINKS
Rachman Clinic

TikTok @dr.brad.rachman
Instagram @rachmanclinic
YouTube @drbradrachman
LinkedIn linkedin.com/company/rachman-clinic

In this episode, I sit down with Dr. Nathan Bryan, one of the world’s leading researchers in nitric oxide physiology and a pioneer who has reshaped how clinicians think about vascular health, metabolism, and the oral microbiome.

Dr. Bryan began his career as a drug discovery chemist, but his work quickly revealed a deeper truth: our ability to generate nitric oxide depends heavily on dietary inputs, oral bacteria, and lifestyle patterns—not just pharmaceuticals. His research uncovered the essential role of the oral microbiome in converting dietary nitrates and nitrites into bioactive nitric oxide, influencing everything from blood pressure to mitochondrial efficiency to immune resilience.

We dig into his groundbreaking contributions, including his founding of Neogenis and the development of the original Neo40 lozenges and nitric oxide indicator test strips, which helped bring NO science into everyday clinical practice. Dr. Bryan also shares how his research has evolved, what most clinicians still misunderstand about nitric oxide biology, and how he’s now advancing the field through his new company, n1o1.com, where he’s translating cutting‑edge nitric oxide science into next‑generation clinical and consumer solutions designed to restore NO production more effectively than ever.

If you’re interested in cardiovascular health, performance, metabolism, or the intersection of the oral microbiome and systemic physiology, this conversation will change the way you think about nitric oxide.

LINKS
Nathan on the Web
Dr. Noseworthy on the Web.
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Host Dr. Steve Nosworthy interviews Dr. Brad Rachman about his journey from a personal autoimmune crisis to decades in functional medicine and laboratory medicine, including his work with Genova Diagnostics. They discuss the history and evolution of functional medicine, how to choose meaningful tests, and how labs can both help and overwhelm clinicians.

Topics include Dr. Rockman’s origin story with ankylosing spondylitis, high-value lab markers (complement C3/C4, MMP‑9, TGF‑β1, GGT, oxidized LDL, CD4/CD8), stealth pathogens (EBV, Coxsackie, Chlamydia pneumoniae), dysglycemia assessment (HOMA, C‑peptide), and practical testing strategy versus data overload.

The conversation also covers clinical models and practice design (volume vs engagement), creating a patient roadmap and 10‑year risk analysis using AI, therapeutic priorities (diet, lifestyle, pro‑resolving mediators), and the philosophy of vitalism — trusting and stewarding the body’s innate ability to self‑regulate.

Listeners can expect practical takeaways on which tests are most actionable, how to communicate with patients about symptom flares, when to prioritize lifestyle over supplements, and how to design care that restores long‑term vitality and resilience.

LINKS
Rachman Clinic

TikTok @dr.brad.rachman
Instagram @rachmanclinic
YouTube @drbradrachman
LinkedIn linkedin.com/company/rachman-clinic

Host Dr. Steve Noseworthy sits down with Dr. Joseph Smith — chiropractic neurologist, founder of Atlas Health and creator of the upcoming Nuvius seminar series — to explore how the brain, hormones and immune system interact to drive chronic illness and recovery. They discuss Joseph’s clinical evolution, credentials and the approach behind Nuvius: blending functional neurology with in-exam nutritional trials.

Topics include the neuroendocrine-immune “super-system,” the role of Allostasis, common clinical blind spots, patient belief and behavior, long COVID, gut–brain interactions, and practical bedside exams (12 core tests) you can use immediately. Dr. Smith explains how to localize dysfunction, trial nutrition in real time, and prioritize interventions for faster, safer results.

Listeners can expect a mix of theory and hands-on clinical strategy aimed at clinicians who want pragmatic tools to integrate brain-based assessment and nutrition into everyday practice. For dates and registration, Dr. Smith and Nuvius seminars are available via Apex Seminars and Atlas Health.

LINKS
Dr. Noseworthy on the Web.
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My guest today on the Func Med Nation podcast is Dr. Allison Siebecker, a prominent expert in the field of Small Intestinal Bacterial Overgrowth (SIBO) with a wealth of clinical experience and inudstry accolades. Together we delves into the world of SIBO, exploring its origins, symptoms, and cutting-edge treatments.

In this episode, listeners will uncover Dr. Siebecker's personal journey from a natural health enthusiast to a leading SIBO specialist. Learn about the two main physiological causes of SIBO, the significance of the Migrating Motor Complex, and the surprising role of abdominal adhesions. Discover the intricate dynamics involved in diagnosing and treating this complex condition, including the latest advancements in testing and the efficacy of various treatment protocols.

Dr. Siebecker also shares valuable insights into dietary approaches, emphasizing the importance of individualized treatment plans. Whether you are a clinician or a patient, this episode offers a comprehensive understanding of SIBO and guidance on navigating its challenges.

LINKS
www.siboinfo.com
Dr. Noseworthy on the Web.
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In this captivating episode of the Func Med Nation podcast, host Dr. Steve Noseworthy engages in an in-depth conversation with Dr. Stuart McGill, a professor emeritus from the University of Waterloo and a world-renowned expert in spine function and rehabilitation. Together, they explore Dr. McGill's vast career spanning over three decades, during which he has contributed significantly to understanding lumbar function and back pain.

Dr. McGill shares his professional journey and personal philosophy on health and fitness, highlighted by inspiring anecdotes involving professional athletes and ordinary individuals who have transformed their lives under his guidance. The dialogue transitions from traditional discussions about biomechanics to broader life lessons, touching upon critical misconceptions and the importance of personalized health approaches.

Tune in for a unique episode that looks beyond conventional views on back pain, as Dr. McGill provides insights into optimizing health, understanding one’s body, and striving for holistic well-being. This is an episode rich with knowledge, humor, and yes, a few words about Dr. McGill's iconic mustache.

LINKS

See Dr. McGill on the Web.
Dr. Noseworthy on the Web.
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Join Dr. Steve Noseworthy as he engages in a captivating conversation with Dr. Stuart McGill, a preeminent figure in spine function, injury prevention, and rehabilitation. In this episode, Dr. McGill, a professor emeritus at the University of Waterloo, shares his life's journey, from his extensive academic achievements to his personal commitment to health and fitness.

Explore Dr. McGill's philosophy on maintaining an active lifestyle, his views on training methodologies, and his dedication to helping both athletes and everyday individuals enhance their physical capabilities. Learn how his unique approach to movement competency and body mechanics can transform not just the lives of his patients but also anyone seeking to improve their overall wellness.

This episode is packed with inspiring stories, wisdom on enduring life's physical demands, and engaging anecdotes, including a lighthearted discussion about Dr. McGill's iconic mustache. Don't miss the opportunity to gain valuable insights into achieving a balanced, fulfilling life through enhanced movement and fitness strategies.

LINKS
Dr. McGill on the Web.
Dr. Noseworthy on the Web.
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In this episode of Func Med Nation, Dr. Steven Noseworthy, DC, welcomes Dr. Russell Jaffe, MD-PhD, a highly esteemed physician, researcher, and thought leader in integrative and functional medicine. Dr. Jaffe shares his remarkable personal and professional journey from conventional Western medicine to a comprehensive, eclectic approach that honors multiple healing traditions.

Dr. Jaffe discusses his transformative seven-year apprenticeship in traditional Chinese medicine, along with his deep integration of yoga and Ayurveda into clinical practice. These experiences fundamentally reshaped his medical worldview, highlighting the power of blending diverse medical philosophies to achieve better patient outcomes.

Listeners will gain profound insights into the value of integrative medicine, the importance of personalized and systems-based care, and practical lessons on bridging Eastern and Western approaches in modern functional medicine.

Key Topics:

• Dr. Jaffe’s transition from traditional Western medicine to integrative practices
• Seven-year apprenticeship in Traditional Chinese Medicine
• Integration of yoga and Ayurveda into clinical care
• The significance of blending diverse medical traditions
• Lessons for functional medicine practitioners seeking a broader, patient-centered perspective

This conversation offers inspiration and practical wisdom for clinicians interested in expanding their therapeutic toolkit through cross-cultural medical insights.

LINKS
Russell on the Web
Dr. Noseworthy on the Web.
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Why is the brain's role in immune regulation often overlooked compared to its control over the gut and hormones? Join us on Func Med Nation as we tackle this thought-provoking question with our esteemed experts Drs. Peter Scire and Rob Melillo. Together, we navigate the intriguing concept of immunosception and its vital influence on neuroimmune communication, drawing from the groundbreaking research of Kevin Tracey. As we explore the brain's impact on the immune system, we raise awareness about the critical role of neuroimmune interactions and the potential "immuno homunculus," a proposed map of these connections.

Our discussion extends into the fascinating realms of interoception and brain lateralization. We uncover how the brain perceives internal bodily states to maintain homeostasis, linking these perceptions to emotional and developmental experiences. Discover how right-brain development during early childhood can influence immune function and self-tolerance, with potential implications for understanding conditions like autism and autoimmune diseases. Peter and Rob share clinical insights, emphasizing the need for a holistic approach that values clinical presentations over standard lab tests in diagnosing immune-related issues.

The episode is Part 3 of a series and concludes with an exploration of the insular cortex and its role in neuroimmune interactions. We shed light on the challenges of interpreting immune responses through lab tests, especially for complex conditions. By examining real-life case studies and the intricacies of brain-immune communication, we aim to inspire Functional Medicine practitioners to deepen their understanding of this interconnected system. Join us for an enlightening conversation that bridges neuroscience and immunology, encouraging a more integrated approach to health and healing.

LINKS
Get the Disconnected Kids book on Amazon
Dr. Melillo on the web: https://www.drrobertmelillo.com/
Dr. Scire on the web: http://drscire.com/
Dr. Noseworthy on the Web.
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