Gastroenterology

Advances in the understanding of the hepatitis C virus (HCV) life cycle have led to the development of many promising direct-acting antiviral agents (DAA) in the last decade. An editorial in the December issue of Gastroenterology looks at the development of DAAs directed at multiple targets in the HCV life cycle and asks, “Are we ready for interferon-free treatment regimens?” Dr. Kuemmerle speaks to editorial co-author Dr. Anna S. Lok of the University of Michigan Health System; Plus, a rundown of top stories from this month's issue of GI and Hepatology News.

A study in the November issue of Gastroenterology looks at the risk of nonmelanoma skin cancer (NMSC) among individuals with inflammatory bowel disease (IBD), including those with or without exposure to immunosuppressant medications.  Dr. Kuemmerle speaks to author Dr. Harminder Singh of the University of Manitoba; Plus, a rundown of top stories from this month's issue of GI and Hepatology News.

A study in the October issue of Gastroenterology evaluated the prevalence of celiac disease (CD) antibodies and biopsy-confirmed CD among patients with nonconstipated irritable bowel syndrome (NC-IBS) in a large US population. Dr. Kuemmerle speaks with author Dr. Brooks D. Cash of the National Naval Medical Center, Bethesda, Maryland.  Plus, a rundown of top stories from this month's issue of GI and Hepatology News

Two studies in the September issue of Gastroenterology look at the effects of vertical sleeve gastrectomy (VSG) on metabolism. The first study examines whether or not beneficial effects of VSG on plasma lipid levels are weight independent.  The second study investigated alterations in glucose metabolism in rats following Roux-en-Y gastric bypass (RYGB) and VSG.  Dr. Kuemmerle speaks to two co-authors of both studies, Dr. Randy J. Seeley and Dr. Darleen A. Sandoval, both of the University of Cincinnati Metabolic Diseases Institute; Plus, a rundown of top stories from this month's issue of GI and Hepatology News.

A study in the August issue of Gastroenterology assessed long-term rates of eradication, durability of neosquamous epithelium, disease progression, and safety of radiofrequency ablation in patients with Barrett's esophagus. Dr. Kuemmerle speaks to author Dr. Nicholas Shaheen of the University of North Carolina Chapel Hill School of Medicine and Public Health; Plus, a rundown of top stories from this month's issue of GI and Hepatology News.

Two studies in the July issue of Gastroenterology examine the relationship between fruits, vegetables, folate, and colorectal cancer, and suggest that potential associations are more complex than initially considered. Dr. Kuemmerle speaks to the author of an editorial on these papers, Dr. Andrew T. Chan of Massachusetts General Hospital; Plus, a rundown of top stories from this month's issue of GI and Hepatology News.

A review in the June issue of Gastroenterology discusses the effects of autophagy on hepatic and pancreatic physiology, and the contribution of this degradative process to diseases of the liver and pancreas. Dr. Kuemmerle speaks with author Dr. Mark Czaja of the Albert Einstein College of Medicine.  Plus, a rundown of top stories from this month's issue of GI and Hepatology News.

A study in the May issue of Gastroenterology examines the influence of aspirin and NSAID use on risk of diverticulitis and diverticular bleeding in a large prospective cohort. Dr. Kuemmerle speaks with author Dr. Lisa Strate of the University of Washington School of Medicine.  Plus, a rundown of top stories from this month's issue of GI and Hepatology News.

A comprehensive review on recent findings about the clinical features, diagnosis, epidemiology, pathophysiology, and treatment of microscopic colitis appears in the April issue of Gastroenterology. Dr. Kuemmerle speaks with a co-author of this “Reviews in Basic and Clinical Gastroenterology” article, Dr. Darrell S. Pardi of the Mayo Clinic College of Medicine, Rochester, Minnesota.  Plus, a rundown of top stories from this month's issue of GI and Hepatology News.

The AGA releases its medical position statement and technical review on the management of Barrett's esophagus in the March issue of Gastroenterology. Dr. Kuemmerle speaks with a co-author of both documents, Dr. John Inadomi of the University of Washington School of Medicine, about the development of the guidelines.  Plus, a rundown of top stories from this month's issue of GI and Hepatology News.