Gastroenterology

A study in the February Gastroenterology looks at changes in insulin resistance and weight in patients with chronic hepatitis C during and after peginterferon and ribavirin therapy.  Dr. Kuemmerle speaks with lead author Dr. Hari S. Conjeevaram of the University of Michigan.  Plus, a rundown of top stories from this month's issue of GI and Hepatology News.

An important prospective study in the January Gastroenterology sought to define  define the prevalence of both nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) among a largely middle-aged group of outpatients.  Dr. Kuemmerle speaks to author Dr. Stephen A. Harrison of the Brooke Army Medical Center in Fort Sam Houston, Texas, about the study's findings; plus, a rundown of top stories from this month's issue of GI and Hepatology News.

A Pyrosequencing study in the December Gastroenterology looked at the role of gastrointestinal microbiota in the etiology of inflammatory bowel diseases (IBD).  Compositions of microbial communities were examined in 40 pairs of twins who were concordant or discordant for Crohn's disease (CD) and ulcerative colitis (UC).  Dr. Kuemmerle speaks to Dr.  Lars Engstrand of the Swedish Institute for Infectious Disease Control;  plus, a rundown of top stories from this month's issue of GI and Hepatology News.

A study in the November issue of Gastroenterology investigates whether detection of proximal nondysplastic serrated polyps (ND-SP) at screening and surveillance colonoscopies is associated with advanced neoplasia.  Dr. Kuemmerle speaks with author Dr. David Lieberman from the Portland VA Medical Center and Oregon Health and Science University.  Plus, a rundown of top stories from this month's issue of GI and Hepatology News.

A review article in the October 2010 issue of Gastroenterology looks at the mechanism of action of proton pump inhibitors, summarizes the data available on the putative adverse effects of PPI therapy, and proposes guidelines for clinicians who prescribe these agents to limit the potential for adverse outcomes.  Dr. Kuemmerle speaks to co-author Dr. David Metz of the University of Pennsylvania School of Medicine. Plus, a rundown of top stories from this month's issue of GI and Hepatology News.

Using a novel simultaneous acoustic cough recording and impedance/pH monitoring technique, the authors of a study in the September issue of Gastroenterology explored the temporal association between cough and gastroesophageal reflux (GOR) in patients in whom non-GOR causes have been excluded.  Dr. Kuemmerle speaks to author Dr. Jaclyn A. Smith of the University of Manchester. Plus, a rundown of top stories from this month's issue of GI and Hepatology News.

Achalasia is the subject of a mini-review article in the August issue of Gastroenterology.  Dr. Kuemmerle speaks to author Dr. David Katzka of the Mayo Clinic, Rochester, MN about factors including pathophysiology, diagnosis and treatment of the disease.  We also begin a new feature this month highlighting important stories and topics from the August issue of GI and Hepatology News, the AGA's official newspaper.

A prospective study to determine the clinical, pathologic, and serologic spectrum of celiac disease in a general population appears in the July issue of Gastroenterology. Dr. Kuemmerle speaks to authors Dr. Marjorie M. Walker of Imperial College London and Dr. Joseph A. Murray of the Mayo Clinic, Rochester, Minnesota.

A study in the June 2010 issue of Gastroenterology sought to identify the incidence and predictors of de novo gastroesophageal variceal formation and progression in a large cohort of patients with chronic hepatitis C and advanced fibrosis.  Dr. Kuemmerle speaks with the author of this article, Dr. Robert J. Fontana of the Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical School. 

An article in the May 2010 issue of Gastroenterology reflects on the 2008 multi-society guidelines for colorectal cancer (CRC) screening, stressing that doctors should keep an open mind and consider all evidence when deciding which test to recommend for patients.  Dr. Kuemmerle speaks with the author of this “Mini-Reviews and Perspectives” article, Dr. James E. Allison, Clinical Professor of Medicine Emeritus at the University of California, San Francisco.