Genetics (Audio)

Genetics (Audio) episodes:

• 11.14.2023

  CARTA: Comparative Anthropogeny - A Weakly Structured Stem for our Origins in Africa with Brenna Henn

  We know Homo sapiens started in Africa, but we're uncertain about how they spread. Limited fossils and data have hindered our understanding. I'll discuss popular theories about our origins and how recent genetic data from Khoe-San people in southern Africa...

  
• 10.23.2023

  Translating Cell Therapies to Clinical Realities with Malcolm Moos Jr. - Breaking News in Stem Cells

  Are you curious about the future of medical treatments and how they might impact your health? Malcolm Moos, Jr., M.D., Ph.D., shares how cellular therapies are revolutionizing medical treatments. Explore how cells hold the potential to provide new hope for...

  
• 09.30.2023

  Genomics for Everyone: UCSC Researchers Release First Human Pangenome

  UC Santa Cruz scientists, along with a consortium of researchers, have released a draft of the first human pangenome—a new, usable reference for genomics that combines the genetic material of 47 individuals from different ancestral backgrounds to allow for a...

  
• 08.17.2023

  Spatial Analysis of RNA Distribution During Early Mouse and Human Embryogenesis - Elsy Buitrago-Delgado

  Elsy Buitrago-Delgado, Ph.D., shares how spatial analysis of RNA distribution during early mouse embryogenesis suggests that the first cell fate choice is made at the 4-cell stage. She also discusses how notch signaling regulates cell fate choices during early human...

  
• 08.12.2023

  Navigating Challenges in Genomics and Patient Advocacy

  The Science & Technology Ethics Center (STEC) is proud to present a series of lectures and a panel discussion that explores the intersection of genomics, medical ethics, and patient rights. This thought-provoking session delves into the ethical considerations surrounding genetic...

  
• 07.27.2023

  Unraveling the Role of Histone Deacetylation during Cell Division

  The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities....

  
• 02.22.2023

  CARTA: Imagining the Future of Anthropogeny with Evan Eichler and Daniel Geschwind

  Anthropogeny, has provided many new discoveries over the past decade, ranging from new fossil finds to ancient DNA data, including from extinct hominins. This CARTA symposium highlights where future efforts should be focused and what type of novel collaborations are...

  
• 02.20.2023

  CARTA: Imagining the Future of Anthropogeny with Pascal Gagneux Robert Kluender Anne Stone

  Anthropogeny, has provided many new discoveries over the past decade, ranging from new fossil finds to ancient DNA data, including from extinct hominins. This CARTA symposium highlights where the future efforts should be focused and what type of novel collaborations...

  
• 02.10.2023

  CARTA: Imagining the Future of Anthropogeny with Terry Sejnowski and Sarah Tishkoff

  Anthropogeny, has provided many new discoveries over the past decade, ranging from new fossil finds to ancient DNA data, including from extinct hominins. This CARTA symposium highlights where the future efforts should be focused and what type of novel collaborations...

  
• 01.13.2023

  Prostate Cancer Genetics and Genomics - Prostate Cancer Patient Conference 2022

  As part of the 2022 Prostate Cancer Patient Conference, Dr. Jonathan Chou discusses the role of genetics and genomics in prostate cancer. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Education] [Show ID: 38560]

  
• 12.21.2022

  CARTA: Imagining the Future of Anthropogeny - African Genomic Analyses Shed Light on Human Evolutionary History with Sarah Tishkoff

  Africa is thought to be the ancestral homeland of all modern human populations within the past 300,000 years. It is also a region of tremendous cultural, linguistic, climatic, and genetic diversity. Despite the important role that African populations have played...

  
• 12.17.2022

  CARTA: Imagining the Future of Anthropogeny - Ancient DNA and Anthropogeny with Anne Stone

  The first Neandertal DNA was recovered 25 years ago, and since then, ancient DNA has provided many surprising insights into human evolutionary history. Among these are the discoveries of the multiple admixture events among late Pleistocene humans and the remnants...

  
• 12.10.2022

  CARTA: Imagining the Future of Anthropogeny - Genome Structure Variation and the Evolution of Human Specific Genes with Evan Eichler

  The discovery and resolution of genetic variation is critical to understanding disease and evolution. Our most recent work sequences diverse human and nonhuman primate genomes using both ultra-long and high-fidelity long-read sequencing technologies. Advances in this area have made possible...

  
• 07.08.2022

  Can Big (Microbiome) Data Save the World? – Using AI and Microbiome Data to Predict Health Outcomes

  Our bodies are dynamic ecosystems housing trillions of microbes that, while invisible to the naked eye, play a critical role in shaping human health. Scientists are just beginning to understand the superpowers the microbiome holds. In this program Marina Sirota,...

  
• 06.18.2022

  CARTA - Humans: The Planet-Altering Apes - Loss of Species Loss of Genetic Variation and the Future of Earth’s Biota with Oliver Ryder

  We are experiencing an accelerated rate of loss of species due to human activities. This anthropogenic phenomenon extends beyond extinction. It encompasses an expanded loss of biodiversity as the genetic diversity of species diminish, reducing gene pools to “gene puddles.”...

  
• 06.03.2022

  Sea Urchins and Sea Slugs

  Amazing new technologies in developmental biology and genetics research are allowing scientists to begin to answer long standing questions such as – how does a single fertilized egg cell transform into a complex animal? Why does the embryo of a...

  
• 03.30.2022

  CARTA: Ancient DNA and Human Evolution – Brenna Henn: The Origins of Modern Humans in Africa

  Brenna Henn (Stony Brook Univ) explores patterns of genetic diversity across Africa and models for modern human origins in this talk. She discusses whether genetic data is concordant with archaeological data and suggests directions for future research. Series: "CARTA...

  
• 03.05.2022

  Epithelial Stem Cells and Combined Cell and Gene Therapy - Breaking News in Stem Cells

  Michele De Luca, MD, shares his research in gene therapy for epidermolysis bullosa and cell therapy for ocular burns. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37671]

  
• 02.19.2022

  Evolution of Genome Instability in Cancer with Don Cleveland - Sanford Stem Cell Symposium

  Don Cleveland, PhD, shares new research on the role of chromothripsis, targeting cancers driven by ecDNA and more. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37586]

  
• 02.16.2022

  Genomics - Sanford Stem Cell Symposium

  Dan Kaufman, MD, PhD, David Traver, PhD, Gene Yeo, PhD, MBA, discuss the impact of genomics in relation to stell cell research including potential therapeutics for MDS and the role of the somite in hematopoietic stem cell fate. Series:...

  
• 02.14.2022

  RNA Binding Proteins: A Splicing Story in IPSC Models of MDS with Gene Yeo - Sanford Stem Cell Symposium

  There are at least 2,500 proteins that bind RNA. Gene Yeo, PhD, MBA, explains how his lab studies these RNA binding proteins and their impact on human health. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37589]

  
• 12.11.2021

  Genetics of Autism with Jonathan Sebat PhD

  Jonathan Sebat, PhD shares current research on how combinations of rare gene mutations and complex common variant risk factors contribute to autism. Series: "Autism Awareness Programs" [Health and Medicine] [Science] [Show ID: 37658]

  
• 09.04.2021

  CRISPaper: Understanding CRISPR Gene-Editing through Art

  To Sheng-Ying Pao, the power of reframing CRISPR lies in what is absolutely ordinary: paper. In CRISPaper, Pao revisited a cultural past in the ancient art of papermaking. In ancient China, wild rice was used to make paper. Pao took...

  
• 08.20.2021

  UCSF Berkeley UCLA to Launch Sickle Cell Trial Using CRISPR

  UC Consortium launches first clinical trial using CRISPR to correct the gene defect that causes Sickle Cell Disease. Dr. Mark Walters of UCSF talks about a new CRISPR gene therapy developed by scientists and physicians at UC Berkeley, UCSF and...

  
• 07.08.2021

  CARTA: The Evolution of Human Physical Activity - Herman Pontzer Grazyna Jasienska Ellen Breen

  Human physical activities differ significantly from other species. How, when and why did these capabilities evolve? What adaptations underlie them? And how did the evolution of human physical activity affect other key human characteristics that have advanced our species? Herman...

  
• 07.02.2021

  CARTA: The Evolution of Human Physical Activity - Jandy Hanna -The Rise and Fall of Climbing in Human Evolution

  Human physical activities differ significantly from other species. How, when and why did these capabilities evolve? What adaptations underlie them? And how did the evolution of human physical activity affect other key human characteristics that have advanced our species? Jandy...

  
• 06.26.2021

  CARTA: The Evolution of Human Physical Activity - Herman Pontzer - The Evolution of Human Metabolism

  Human physical activities differ significantly from other species. How, when and why did these capabilities evolve? What adaptations underlie them? And how did the evolution of human physical activity affect other key human characteristics that have advanced our species? Herman...

  
• 06.23.2021

  CARTA: The Evolution of Human Physical Activity - Ellen Breen - A Human Genetic Mechanism for Endurance Running

  Human physical activities differ significantly from other species. How, when and why did these capabilities evolve? What adaptations underlie them? And how did the evolution of human physical activity affect other key human characteristics that have advanced our species? Ellen...

  
• 06.21.2021

  CARTA: The Evolution of Human Physical Activity - Yana Kamberov - Genetic Drivers of Human Thermoregulatory Skin Traits

  Human physical activities differ significantly from other species. How, when and why did these capabilities evolve? What adaptations underlie them? And how did the evolution of human physical activity affect other key human characteristics that have advanced our species? Yana...

  
• 06.21.2021

  CARTA: Cellular and Molecular Explorations of Anthropogeny - Wysocka: Making Faces: Regulatory Evolution and Variation in the Human Neural Crest

  Explores cellular anthropology to understand how variation in human regulatory elements can mediate morphological evolution and individual variation of the craniofacial form. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 32973]

  
• 06.19.2021

  CARTA: The Evolution of Human Physical Activity - Tatum Simonson - Human Adaptation to High Altitudes and Aquatic Environments

  Human physical activities differ significantly from other species. How, when and why did these capabilities evolve? What adaptations underlie them? And how did the evolution of human physical activity affect other key human characteristics that have advanced our species? Tatum...

  
• 05.31.2021

  Precision Genomics and Immunotherapy: Cancer and Beyond - Exploring Ethics

  Breakthroughs in genomics and targeted therapies are revolutionizing the practice of clinical oncology. Precision genomics and immunotherapy offer promise to improve outcomes in cancer, but doing so means we need to move beyond historical models for cancer diagnosis and treatment....

  
• 05.30.2021

  A Closer Look at...Spinal Cord Injury

  Mark Tuszynski, MD, Ph.D., Bob Yant, and Lawrence S.B. Goldstein, Ph.D. discuss the newest research and treatments for spinal cord injury, including how neural stem cells may be leveraged to potentially regain function. Series: "Stem Cell Channel" [Health and...

  
• 04.13.2021

  CARTA: Altered States of the Human Mind: Implications for Anthropogeny: Kenneth Kidd - Alcohol Metabolism and Alcoholism

  Experts address altered states of the mind that are deliberately induced by humans. We will address what is known about origins and mechanisms of these mind-altering practices. In doing so, we hope to gain new insights into the origins and...

  
• 10.19.2020

  Gene Therapy for X-linked SCID - Stephen Gottschalk

  Stephen Gottschalk, MD St. Jude Children's Research Hospital Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36350]

  
• 10.19.2020

  Stem Cell and Gene Therapy - Matthew Porteus Tippi Mackenzie Matthew Spear Stephen Gottschalk

  Stem cells may play a critical role in treating genetic diseases. Hear from experts in the field. Moderated by Matthew Porteus, MD, PhD, Stanford University Tippi MacKenzie, MD, UC San Francisco: Fetal Therapy for Alpha Thalassemia Major Matthew A. Spear, MD, Poseida...

  
• 10.12.2020

  Towards a Cure for IPEX Syndrome: Engineered-Treg Replacement or Stem Cell Gene Editing - Rosa Bacchetta

  Rosa Bacchetta, MD Stanford University Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 36345]

  
• 10.10.2020

  Gene Therapy for Artemis Severe Combined Immunodeficiency (ART-SCID) - Jennifer Puck

  Jennifer M Puck, MD UC San Francisco Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 36329]

  
• 10.10.2020

  Hematopoietic Stem Cell Gene Therapy for Primary Immune Deficiencies - Don Kohn

  Donald B. Kohn, MD UCLA Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36330]

  
• 10.10.2020

  Blood and Immune System Disorders - Crystal Mackall Alysia Vaccaro Jennifer Puck Donald Kohn Mark Walters

  What impacts has stem cell research made for blood and immune system disorders? Hear the latest from experts in the field. Moderated by Crystal Mackall, MD, Stanford University Alysia Vaccaro: Patient Perspective Jennifer M Puck, MD, UC San Francisco: Gene Therapy for...

  
• 10.04.2020

  Gene Correction in Sickle Cell Anemia - Mark Walters

  Mark C. Walters, MD UCSF Benioff Children's Hospital Oakland Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36331]

  
• 10.02.2020

  Fetal Stem Cell Transplantation for Alpha Thalassemia Major - Tippi Mackenzie

  Tippi MacKenzie, MD UC San Francisco Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 36348]

  
• 10.02.2020

  CAR-T Cells: Poseida Therapeutics - Matt Spear

  Matthew A. Spear, MD Poseida Therapeutics Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36349]

  
• 08.22.2020

  Individualized Patient Therapy Stem Cells and Gene Editing

  Dr. Aimee Kao discusses how induced pluripotent stem cells, iPSC's, could offer ways to individualize patient therapy. Dr. Kao then looks at the history of gene editing. [Health and Medicine] [Show ID: 36270]

  
• 06.15.2020

  The Evolution of SARS-CoV-2

  In this presentation from the course The Evolution of Infectious Diseases, professor of biology and infectious disease researcher Justin Meyer provides a detailed overview of the previous, current and future evolution of the SARS-CoV-2 virus. Series: "The Evolution of Infectious...

  
• 11.23.2019

  Your Genetic Privacy in the Big Data Era - Exploring Ethics

  In the United States, privacy is considered a fundamental right. Yet today our activities are followed to a degree unfathomable not long ago by way of cell phones, online behaviors, and more. As genomic technologies continue to expand, another avenue...

  
• 11.08.2019

  Sensory Implications of Brain Organoids with Patricia Churchland

  What defines consciousness? Can it develop in a petri dish? Patricia Churchland reviews the current state of brain organoid research and shares her views on how conciseness and physical structures within the brain intersect. She also cautions the media on...

  
• 11.01.2019

  The Current Status of Human Brain Organoids Research with Alysson Muotri and Larry Goldstein

  The study of brain organoids is leading to a better understanding of human development and potential therapies for neurological disorders. Yet when people hear the phrase "brain in a dish" it instantly brings to mind the stuff of science fiction...

  
• 10.29.2019

  Stem Cells to the Rescue: Saving the Northern White Rhino from Extinction

  There are only two Northern White Rhinos left on the planet. How can we reverse extinction to save them and use the lessons learned to help other endangered species? Marisa L. Korody, PhD of the San Diego Zoo Institute for...

  
• 10.26.2019

  Editing the Code of Life: Into the Future with CRISPR Technology with Jennifer Doudna - 2019 Nierenberg Prize for Science in the Public Interest

  Jennifer Doudna, co-discoverer of CRISPR-Cas9 and winner of the 2022 Nobel Prize in Chemistry, discusses how genome editing with CRISPR technology is transforming biology. CRISPR-Cas9, an RNA-guided enzyme with remarkable abilities to recognize and cleave DNA, operates by mechanisms that...