GI Pearls Podcast

Show Notes for May 2019 – Episode 32

* Risk of postpolypectomy bleeding with uninterrupted clopidogrel therapy- an industry-indepentend, double-blind, randomized trial. – Gastroenterology* Personalised surveillance for serrated polyposis syndrome: results from a prospective 5-year international cohort study – GUT* Cold snare endoscopic resection of nonpedunculated colorectal polyps larger than 10mm: A systematic review and pooled analysis – GIE* Weight Regain After Bariatric Surgery-A Multicentre Study of 9617 Patients from Indian Bariatric Surgery Outcome Reporting Group. – Obesity Surgery* Resolution of NAFLD after bariatric surgery – CGH* Risk of bacterial exposure to the endoscopist’s face during endoscopy – GIE* Low Prevalence of Suspected Barrett’s Esophagus in patients with GERD without Alarm Symptoms – CGH* Efficacy of  induction therapy with high intenstity Tofacitinib in 4 patients with acute severe UC – CGH* Fecal Microbial Transplant Capsules are Safe in Hepatic Encephalopathy: A Phase 1, Randomized, Placebo-Controlled Trial. – Hepatology* Illuminating Elimination Diets: Controversies Regarding  Dietary Treatment of Eosinophilic Esophagitis – Dig Dis Sci

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Show Notes for April 2019 – Episode 31

* Prediction of individuals at high absolute risk of esophageal squamous cell carcinoma – GIE* Updates on Gastric Intestinal Metaplasia – Digestive Diseases Sci* Thermal ablation of mucosal defect margins reduces adenoma recurrence after colonic EMR – Gastro* Transfusion Strategies for Acute Upper Gastrointestinal Bleeding – NEJM * Effect of restrictive versus liberal transfusion strategies on outcomes in patients with cardiovascular disease – BMJ * Outcomes following restrictive or liberal red blood cell transfusion in patients with lower gastrointestinal bleeding – AP&T* Predicting the Course of Disease in Hospitalized  Patients With Acute Severe Ulcerative Colitis – IBD* Fecal Microbiota Transplantation Is Superior to  Fidaxomicin for Treatment of Recurrent Clostridium difficile Infection – Gastro* Hepatocellular Carcinoma – NEJM* Non-invasive assessment of liver disease in patient with NAFLD. – Gastroenterology* No association between pseudopolyps and colorectal neoplasia in patients with IBD – Gastro * Endoscopic sleeve gastroplasty versus laparoscopic sleeve gastrectomy: A case matched study. – GIE* Glucocorticosteroids for people with alcoholic hepatitis. –  Cochrane Database Syst Rev.* Switching between biologics and biosimilar in IBD – CGH* Preventive medicine in IBD – CGH

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Show Notes for March 2019 – Episode 30

Sorry, but I was sick, so episode is shorter, and … late.

* Evaluation of adenomas per colonoscopy and adenomas per positive participant as new quality parameters in screening colonoscopy – GIE* Adherence to Recommended Inpatient Hepatic Encephalopathy  Workup – J Hosp Med* Clinical ipact and Safety of Anticoagulants for portal vein thrombosis – Am J Gastro* Fracture risk in Patients with IBD: Nationwided population cohort study – Am J Gastro* Comparing adenoma and polyp miss rates for total underwater colonoscopy versus standard CO2 – randomized trial using tandem colonoscopy approach.–  GIE* Increasing adenoma detection rate in the right side of the colon comparing retroflexion with a second forward view: review – GIE* Effects of bowel preparation on the human gut microbiome and metabolome– Scientific Reports

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Show Notes for February 2019 – Episode 29

* Effect of FMT on 8-week remission in patients with Ulcerative Colitis – RCT – JAMA * Inflammatory bowel disease increases the risk  of Parkinson’s disease – Gut* Predictors of Metastases in Rectal  Neuroendocrine  Tumors: Results of a National Cohort  Study – Dis Colon Rectum.* Long-term Risk of Colorectal Cancer and Related  Deaths After a Colonoscopy With Normal Findings – JAMA Internal Med* Single-stage EUS-guided choledochoduodenostomy using a lumen-apposing metal stent for malignant distal biliary obstruction – GIE * Refractory ascites in Liver Cirrhosis – Am J Gastro* Choosing the right through-the-scope clip: a rigorous comparison… – GIE* Emergent Colon Resections: Does  Surgeon Specialization Influence Outcomes? – Diseases of Colon&Rectum* Dietary Gluten Intake and Risk of Microscopic Colitis in US women without Celiac Disease – Prospective Cohort Study – Am J Gastr* To scope or not to scope? The safety of Upper Endoscopy in the Setting of Pulmonary Embolism. – Am J Gastr

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Show Notes for January 2019 – Episode 28

* Diagnosis and treatment of definitive diverticular hemorrhage – AmJGastro* Proton-pump inhibitor prophylaxis in the ICU – NEJM* Effectiveness and Safety of Reference  Infliximab and Biosimilar in Crohn Disease: A French Equivalence Study – Annals of IM* Laparoscopic magnetic sphincter augmentation versus double-dose PPI for GERD, randomized controlled trial – GIE* Evolving considerations for thiopurine therapy for IBD – Clinical Practice Update: Commentary – Gastro* Incidence, risk factors and clinical effects of recurrent diverticular hemorrhage: a large cohort study – Gastro* Etiological spectrum and response to endoscopic balloon dilation in patients with benign gastric outlet obstruction – GIE* Pancreatic Cancer Following acute pancreatitis: a population-based matched cohort study – AmJGastro* Trainee colonoscopy quality is influenced by the independent and unobserved performance characteristics of supervising physicians – Endoscopy International Open* Tofacitinib Induction Therapy Reduces Symptoms  Within 3 Days for Patients With Ulcerative Colitis – CGH* Telehealth-Based Evaluation identifies Patients who are not candidates for liver transplantation – CGH* An RCT comparing efficacy of early video capsule endoscopy with standard of care in the approach to nonhematemesis GI bleeding – GIE

Feel free to leave comments about the episode or the articles online at GIpearls.com – just go to the individual episode page.

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Show Notes for December 2018 – Episode 27

* Efficacy of ustekinumab for inducing endoscopic healing in patients with Crohn’s disease – Gastro* Association of Oral Anticoagulants and Proton Pump Inhibitor Cotherapy With Hospitalization for Upper Gastrointestinal Tract Bleeding – JAMA* Clinician Guide to Microbiome Testing – Dig Dis Sci* Stopping 5-ASA in patients with UC starting biolocig therapy does not increase risk of adverse clinical outcomes – Gut Journal* Effect of Aspirin on disability-free survival in the healthy elderly. – NEJM* Hyperbaric oxygen therapy for UC patients hospitalized for moderate-severe flares – Am J Gastro* Mortality due to cirrhosis and liver cancer in the United  States, 1999-2016: observational study – BMJ * No association between screening for HCC and reduced cancer-related mortality in patietns with Cirrhosis –  Gastro* Exposure concentrations of infants breastfed by women receiving biologic therapies for IBD  – Gastro* Comparative effectiveness and safety of Bariatric Procedures for Weight loss – Annals of IM* Risk of esophageal adenocarcinoma after anti-reflux surgery in patients with GERD – Jama Oncology* Guideline – Screening for CRC in individuals with family history of nonhereditary colorectal cancer or adenoma – Gastro

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Show Notes for November 2018 – Episode 26

I’ve changed the intro music, obviously, let me know if you are annoyed by it or like it. Here is the list of papers:

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Acute Liver Failure of Indeterminate Etiology – Am J Gastro

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Efficacy of G CSF and NAC in patients with severe alcoholic hepatitis – CGH

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The vermiform appendix impacts the risk of developing parkinson’s disease. – Science Trans Med

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Water exchange colonoscopy increases ADR: Systematic Review with network Meta-analysis of RCTs – GIE

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Inspection of Endoscope instrument channels after reprocessing using a prototype borescope – GIE

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Real-Time Use of Artificial Intelligence in  Identification of Diminutive Polyps During Colonoscopy – Annals of Int Med

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Comparative efficacy and tolerability of pharmacological agents for management of mild to moderate UC – Lancet Gastro Hep

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Prediction Model for Mortality and Adverse Outcomes Among Patients With Peripheral Eosinopenia on Admission for Clostridium difficile Infection – JAMA surgery

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Methotrexate Is Not Superior to Placebo in Maintaining Steroid-Free Response or Remission in Ulcerative Colitis – Gastro

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Low-Dose Methotrexate for the Prevention of Atherosclerotic Events– NEJM

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Increased Long-term Dietary Fiber intake is associated with decreased risk of Fecal incontinence in Older Women – Gastro

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Primary Biliary Cholangitis: 2018  Practice Guidance – Hepatology

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Efficacy and Safety of Curcumin in treatment of Intestinal Adenomas in Patients with FAP – Gastro

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The Essential Medicinal Chemistry of Curcumin – Journal of Medicinal Chemistry

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Probiotics for Children with Gastroenteritis – NEJM

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Everything is awesome: Don’t forget the Lego – J of Peds and Child Health.

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Show Notes for October 2018 – Episode 25

Also, please sign up for the mailing list on the website at www.gipearls.com 

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Complications of antireflux surgery – Am J Gastro

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Helicobacter Pylori infection is associated with reduced risk of Barrett’s – Am J Gastro

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Reverse Hybrid and Bismuth therapy for Hpylori infection – CGH

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Long-term outcomes of patients with HCV-associated Cryoglobulinemic Vasculitis after Virologic Cure – Gastro

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Tumor Seeding Associated with Selected GI endoscopic interventions – CGH

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Among patients with NAFLD, modest Alcohol use is associated with less improvement in histologic steatosis and steatohepatitis – CGH

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ACG Monograph on Management of IBS – Am J Gastro

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Yield of Colonoscopy after a positive result from FIT – CGH

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Model to determine risk of pancreatic cancer in patients with new onset diabetes – Gastro

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Impact of chromoendoscopy for surveillance of the duodenum in pations with MUTYH and FAP – GIE

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Factors that contribute to indeterminate results from Q-gold in-tube test in patients with IBD – CGH

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Lessons from Using Culture-Guided Treatment after referral for Failure of Tx for Hpylori – CGH

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Acute Liver Failure of Indeterminate Etiology – Am J Gastro

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Show Notes for September 2018 – Episode 24

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Association between portosystemic shunts and increased complications and mortality in patients with cirrhosis  – Gastro

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Safety and efficacy of elobixibat for chronic  constipation–  The Lancet: Gastro

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Oral Anticoagulation in Patients With Liver Disease – JACC

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Risk of Serious and Opportunistic Infections Associated With Treatment of Inflammatory Bowel Diseases – Gastro

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Risk of Oral and Upper GI cancer in FIT-positive Colorectal cancer screening program. – CGH

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Extraintestinal Manifestations in Vedolizumab and  Anti-TNFTreated Patients With Inflammatory Bowel Disease – IBD Journal

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Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features – Cell

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Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT – Cell

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Beyond O&P Times Three – Am J Gastro

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Helicobacter Pylori Infection Does Not Protect Against Eosinophilic Esophagitis – Am J Gastro

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Show Notes for August 2018 – Episode 23

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Long-term effectiveness of Sigmoidoscopy Screening on Colorectal cancer Incidence and mortality in Women and Men – Annals of IM

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Enteral nutriton and quality of life in patients undergoing chemoradiotehrapy for esophageal carcinoma. – GIE

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Outcomes of endoscopic intervention for overt GI bleeding in severe thrombocytopenia – GIE

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Office Management of Hemorrhoids – Am J Gastro

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Childhood BMI and risk of IBD in adulthood: cohort study – Am J Gastro

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Who is wrong? Responses to Kwo et al. – Am J Gastro

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The Cochrane Review Conclusion for Hepatitis C DAA Therapies is Wrong – Am J Gastro

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Direct-acting antivirals for chronic hepatitis C – Cochrane Review

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Practical guidance on the use of faecal calprotectin – Frontline Gastro

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Crohn’s giudelines – Am J Gastro

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Randomized trial comparing the Franseen and Fork-tip needles for EUS-guided fine needle biopsy – GIE

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Hot snare polypectomy with or without saline solution/epi lift for complete resection of small polyps. – GIE

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Association between portosystemic shunts and increased complications and mortality in patients with cirrhosis – Gastro

Yes there are no podcasts between May 2018 and August 2018.

Please e-mail me at info at gipearls.com if you have suggestions for papers to discuss, or comments/concerns.

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