Show Notes for August 2018 – Episode 23

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Long-term effectiveness of Sigmoidoscopy Screening on Colorectal cancer Incidence and mortality in Women and Men – Annals of IM

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Enteral nutriton and quality of life in patients undergoing chemoradiotehrapy for esophageal carcinoma. – GIE

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Outcomes of endoscopic intervention for overt GI bleeding in severe thrombocytopenia – GIE

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Office Management of Hemorrhoids – Am J Gastro

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Childhood BMI and risk of IBD in adulthood: cohort study – Am J Gastro

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Who is wrong? Responses to Kwo et al. – Am J Gastro

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The Cochrane Review Conclusion for Hepatitis C DAA Therapies is Wrong – Am J Gastro

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Direct-acting antivirals for chronic hepatitis C – Cochrane Review

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Practical guidance on the use of faecal calprotectin – Frontline Gastro

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Crohn’s giudelines – Am J Gastro

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Randomized trial comparing the Franseen and Fork-tip needles for EUS-guided fine needle biopsy – GIE

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Hot snare polypectomy with or without saline solution/epi lift for complete resection of small polyps. – GIE

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Association between portosystemic shunts and increased complications and mortality in patients with cirrhosis – Gastro

Yes there are no podcasts between May 2018 and August 2018.

Please e-mail me at info at gipearls.com if you have suggestions for papers to discuss, or comments/concerns.

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Show Notes for May 2018 – Episode 22  – Peptic ulcers, Infections in IBD, EOE, dyspepsia, Infliximab, Pancreatic cysts. etc. Email me – [email protected] if you want to meet up at DDW

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 Effects of Gastroprotectant drugs for the prevention and treatment of peptic ulcer disease and its complications: a meta-analysis of randomised trials – Lancet Gastro

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Non-Cdiff Bacterial infections are reare in patients with flares of IBD – CGH

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Effectiveness of cap-assisted device in removal of food bolus obstruction from esophagus – GIE

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Management of dyspepsia – JAMA

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Infliximab dose intensification in Crohn’s disease – Gastro

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Association of Vedolizumab Level, anti-drug antibodies, and A4B7 occopancy w/ resposne in IBD – CGH

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ACG clinical guideline: Pancreatic Cysts – AmJGastro

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AGA High Value Care – role of IBD Panel in diagnosis and treatment – CGH

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No significant association between proton pump inhibitor use and risk fo stroke – Gastro

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Liver transplantation for locally advanced  intrahepatic cholangiocarcinoma treated with neoadjuvant  therapy  – the Lancet Gastro

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Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence – JAMA

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Show Notes for April 2018 – Episode 21

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Use of N-acectylcysteine plus simethicone to improve mucosal visibility during upper GI endoscopy: a double-blind, randomized controlled trial – GIE

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An International multicenter study evaluating the clinical efficacy and safety of POEM in octagenarians – GIE

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Nut Consumption and Survival in Patients With Stage III Colon Cancer: Results From CALGB 89803 (Alliance) – J of Clin Onc

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Total Pancreatectomy and Islet Autotransplant in the Treatment of Chronic Pancreatitis: Tread very, very carefully. – AmJGastro

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Association of gastric intestinal metaplasia and East Asian ethnicity with risk of gastric adenocarcinoma in a US population. – GIE

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Distritubted hepatocytes expressing telomerase repopulate the liver in homeostasis and injury. – Nature

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Long-Term Safety of In Utero Exposure to Anti-TNFα Drugs for the Treatment of Inflammatory Bowel Disease: Results from the Multicenter European TEDDY Study – AM J Gastro

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Metabolic Slowing and Reduced Oxidative Damage with Sustained Caloric Restriction Support the Rate of Living and Oxidative Damage Theories of Aging – Cell Metabolism

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Neuromodulators for Functional Gastrointestinal Disorders: Rome Foundation Working Team report. – Gastro

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Colonoscopy and Colorectal Cancer Mortality in the Veterans Affairs Health Care System – Annals of IM

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Bouveret’s Syndrome – NEJM

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Regional Patterns of Olmesartan Prescription and the prevalence of duodenal villous Atrophy – CGH

Don’t forget to send your e-mail to [email protected]  for the mailing list.

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Show Notes for April 2018 – Episode 20

Sorry for Audio Quality. I had a cold.

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Volatile Organic Compounds in Feces Associate With  Response to Dietary Intervention in Patients With Irritable Bowel  Syndrome – CGH

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Helicobacter pylori Eradication Reduces Risk for Metachronous Gastric Cancer in High-Risk Patients – NEJM

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Eosinophilic gastroenteritis and other eosinophilic gut diseases distal to the esophagus – Lancet Gastro

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Systematic review with meta-analysis: the worldwide prevalence of Helicobacter pylori infection – AP&T

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The Proposal to Lower P Value Thresholds to .005 – JAMA

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Eliminating In-hospital Fecal Occult Blood Testing: Our Experience with Disinvestment – Am J Medicine

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Use and abuse of faecal occult blood tests in an acute  hospital inpatient setting – Internal Medicine Journal

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Effects of Vedolizumab Therapy on Extraintestinal  Manifestations in Inflammatory Bowel Disease – Dig Disease and Sci

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A Prospective Blinded Study of Endoscopic Ultrasound  Elastography in Liver Disease: Towards a Virtual Biopsy – Clinical Endo

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Appendiceal Pinworms – NEJM

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Loss of Response to Anti‑Tumor Necrosis Factor Alpha  Therapy in Crohn’s Disease Is Not Associated with Emergence of  Novel Inflammatory Pathways – Dig Dis Sci

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 High Prevalence of Barrett’s esophagus and esophageal Squamous Cell Carcinoma after repair of Esophageal Atresia – CGH

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Show Notes for March 2018 – Episode 18

On this epsiode I interview Jay Luther, MD from Massachusetts General Hospital on his Editorial on liver transplantation for alcoholic hepatitis.

Other papers:

* Lesions of all types exist in colon polyps of all sizes. – Am J Gastro

* Abdominal Pain in the Roux-en-Y Gastric Bypass Patient – Am J Gastro

* Metachronous colon polyps in younger versus older adults: a case control study. – GIE

* Risk of metachronous neoplasia on surveillance colonoscopy in young patients with colorectal neoplasia – GIE

* Risk of pancreatitis following treatment of IBS with Eludaxoline – CGH

* Upper GI involvement in children with FAP – GIE

* Alcoholic Liver Disease Guidelines – ACG

* Early liver transplantation for alcoholic hepatitis: Ready for primetime? – Journal of Hepatology

* Jay Luther – MGH

 

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Show Notes for March 2018 – Episode 18

* Effect of Hot Tea Consumption and Its  Interactions With Alcohol and Tobacco Use on the Risk for Esophageal  Cancer – Ann Int Med

* IDSA guidelines for C.diff – IDSA

* Effect of Low-Fat vs Low-Carbohydrate Diet on  12-Month Weight Loss in Overweight Adults – JAMA

* Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria – Science

* Accumulation of Heavy Metals in People on a Gluten-Free Diet – CGH

* Fructans, rather than gluten, indluces symptoms in patients with Non-celiac Gluten sensitivity. – Gastro

* Predictors of post-colonoscopy emergency department use – GIE

* Vedolizumab Concentrations in the Breastmilk of nursing Mothers with IBD – Gastro

* Low Rates of GI and Non-GI complications for Screening and Surveillance Colonoscopies -Gastro

* Hepatitis B virus reactivation during direct-acting antiviral therapy for Hep C – The Lancet Gastro

* Disagreement among gastroenterologists using the Mayo and Rutgeerts Endoscopic scores. – IBD Journal

* Noninvasive imaging biomarker assessment of  liver fibrosis by elastography in NAFLD – Nat Rev GI&Hep

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Show Notes for February 2018 – Episode 17

* Cap cuff-assisted colonoscopy versus standard colonoscopy for adenoma detection: a randomized back-to-back study – GIE

* Risk of Clostridium difficile infection in Patients with Celiac Disease – Am J Gastro

* Faecal microbiota transplantation versus placebo for moderate-to-severe irritable bowel syndrome – Lancet Gastro

* “Weekend Effect” in patients with UGI Hemorrahge: Systematic Review – Am J Gastro

* Sleeve Gastrrectomy vs Rough-en-Y – JAMA

* Bariatric surgery vs obesity with long-term medical complications and obesity related comorbidites. – JAMA

* Reassessing the Safety Concerns of Utilizing Blood Donations from Patients with Hemochromatosis – Hepatology

* PPIs associated with increased mortality in patients with pyogenic liver abscess – AP&T

* Optimal Histologic Cutpoints for Tretment response in Patients with Eosinophilic Esophagitis – CGH

* Pedunculated Laryngeal Hemangioma in a Patient With Suspected Atypical Symptoms of GERD – CGH

* AGA – Acute Pancreatitis Guidelines – Gastro

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Show Notes for January 2018 – Episode 16

* Does rectal diclofenac reduce post-ERCP pancreatitis? A district generalhospital experience – Frontline Gastro

* 2017 IDSA Clinical Practice Guidelines for the Diagnosis & Management of Infectious Diarrhea – Clinical Infect Dis

* Association of Clinician Denial of Patient Requests With Patient Satisfaction – JAMA Int Med

* No association between PPI use and Risk of Alzheimer’s disease – Am J Gastro

* Adherence to Mediterranean Diet and Non-Alcohlolic Fatty Liver Disease: Effect on Insulin Resistance. – Am J Gatro

* Peripheral eosinophilia in patients with IBD defines aggressive disease phenotype – Am J Gastro

* Metal versus plastic stents for anastomotic biliary strictures after liver transplantation: a randomized controlled trial. – GIE

* Adherence to a Healthy Lifestyle is Associated with a Lower risk of Diverticulitis among Men – Am J Gastro

* Abnormal Responses to Local Esophageal Food Allergen Injections in adult patients with Eosinophilic Esophagitis – Gastro

* Cholear vaccine use is associated with a Reduced risk of Death in patients with Colorectal Cancer – Gastro

* Toronto HCC risk index:  A validated scoring system to predict 10-year risk of HCC in patients with cirrhosis – J of Hepatology

* Type A viral Hepatitis: Summary & Update on the molecular virology, epidemiology, pathogenesis and prevention. – J of Hepatology

* Association between early ERCP and mortality in patients with acute cholangitis – GIE

* The EPISOD study: long-term outcomes – GIE

Don’t forget to send me your e-mail address for the mailing list.

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Show Notes for January 2018 – Episode 15

* Colonoscopy Surveillance After Colorectal Cancer Resection – JAMA

* Glucocorticosteroids for people with alcoholic hepatitis. Cochrane Database Syst Rev 2017

* Effects of liraglutide on weight, satiation, and gastric functions in obesity: a randomised, placebo-controlled pilot trial – Lancet Gastro

* Association Between Calcium or Vitamin D Supplementation and Fracture Incidence in Community-Dwelling Older Adults – JAMA

* Platelet Count Does Not Predict Bleding in Cirrhotic Patients: Results from the PRO-LIVER Study – Am J Gastro

* Number of ROM on a colonic transit study does not correlate w/ symptom severity or QOL in chronic constipation – Neurogastro & Motility

* Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database Syst Rev

* Going from A to Z – Clinical Problem Solving – NEJM

* Gavage of fecal sampels from patients with CRC promotes intestinal carcinogenesis in Germ-Free and Conventional Mice – Gastro

* A rare cause of Diarrhea and Polyposis – Gastro

* Effectiveness of endoscopic treatments for colonic diverticular bleeding – GIE

* Dietary trehalose enhances virulence of epidemic Clostridium difficile – Nature

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Show Notes for December 2017 – Episode 14

* Efficacy of a 4-Food Elimination Diet for Children With Eosinophilic Esophagitis  -CGH

* How to obtain and use chromoendoscopy dyes for surveillance colonoscopy in inflammatory bowel disease: a technical guide – GIE

* Endoscopy in inflammatory bowel disease: advances in dysplasia detection and management – GIE

* Endoscopy in inflammatory bowel disease: advances in disease management – GIE

* Randomized sham-controlled trials in endoscopy: a systematic review and meta-analysis of adverse events – GIE

* Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis  – NEJM

* Balloon enteroscopy versus spiral enteroscopy for small-bowel disorders: a systematic review and meta-analysis – GIE

* Association between an increase in blood urea nitrogen at 24 hours and worse outcomes in acute nonvariceal upper GI bleeding – GIE

* Role of capsule endoscopy and fecal biomarkers in small bowel Crohn’s disease to assess remission and predict relapse. GIE

* The Evolution of Procedural Competency in Internal Medicine Training – Jama Int Med

* Risk of Gastrointestinal Bleeding in Patients Taking Non-Vitamin K antagonist anticoagulants – CGH

* Major Bleeding Risk During Anticoagulation with Warfarin, Dabigatran, Apixaban, or Rivaroxaban in Patients with Nonvalvular Atrial Fibrillation. – J of Managed Care & Spec Pharm

* Effects of the 2009 Medical Cannabinoid Legalization Policy on Hospital Use for Cannabinoid Dependency and Persistent Vomiting – CGH

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Efficacy and Safety of Mycophenolate Mofetil and Tacrolimus as Second-line Therapy for Patients With Autoimmune Hepatitis – CGH

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