Could GLP-1s originally designed for diabetes and weight loss influence the risk of developing wet AMD? In this episode of New Retina Radio Journal Club with VBS, host Barton Blackorby, MD, is joined by Katharine Talcott, MD, and Hong-Uyen Hua, MD, to discuss a large national cohort study examining the relationship between GLP-1s and AMD. They explore potential biologic mechanisms, how big-data analyses are shaping retina research, and what these findings could mean for future AMD studies.