Big Picture Science

Going Multicellular


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Imagine life without animals, trees, and fungi. The world would look very different. But while the first life was surely single-celled, we don’t know just how it evolved to multicellular organisms. Two long-term experiments hope to find out, and one has been running for more than 35 years. Hear about the moment scientists watched evolution take off in the lab, and how directed evolution was used to create a multicellular organism. Also, how single embryonic cells become humans, and what all of this says about the possibility of life on other worlds.

Guests:

Jeff Barrick – molecular scientist at the University of Texas at Austin where his lab oversees the Long-Term Evolution Experiment that’s been running since 1988. 

Will Ratcliff – an evolutionary biologist at Georgia Institute of Technology

Ben Stanger – cancer researcher, professor of medicine and developmental biology at the University of Pennsylvania and author of “From One Cell: A Journey into Life’s Origins and the Future of Medicine.”

Joseph L. Graves – evolutionary biologist and geneticist at North Carolina Agricultural and Technical State University and author of “A Voice in the Wilderness: A Pioneering Biologist Explains How Evolution Can Help Us Solve Our Biggest Problems.”

Featuring music by Dewey Dellay and Jun Miyake

Originally aired October 9, 2023

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