Taking hold of something in the physical sense means to grasp securely and with force. In a spiritual sense, taking hold is an intentional decision and an effort to be diligent about something. If we are going to live wisely and victoriously, we have to take hold of spiritual principles. If we are to live that life, we have to be word driven, not culturally driven. Isaiah talks about pursuing and laying hold of the strength of God. When we take hold of the right thing it can bring us into the right place.