Doug Friedman joins the podcast to talk about one of the toughest challenges in biotech—how to survive long enough to actually make an impact. As the head of BioMADE, he's on a mission to build a bioindustrial manufacturing ecosystem that doesn’t just rely on wishful thinking and a single grant check. He explains why most biotech startups get only "one shot on goal" (spoiler: they miss, they’re done) and how we can fix that. Think of it like debugging a bad DNA sequence—you need iteration, not instant perfection. Doug also discusses how government funding is shaping the future of biomanufacturing, why biology today is where semiconductors were in the ‘80s, and why scaling biology might just need its own version of Moore’s Law.

Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?

Learn more at www.messaginglab.com/groweverything 

Chapters:

00:00:00 – Fail Fast or Fail Forever – Why biotech startups need more than one shot on goal

00:00:27 – AI Shake-Up – DeepSeek changes the game (and the stock market) overnight

00:01:01 – China vs. AI – What a hedge fund, government crackdowns, and new algorithms have in common

00:02:19 – Power Hungry AI – Why data centers might outgrow the energy grid before we’re ready

00:03:36 – DeepSeek’s Disruption – What it means for AI, efficiency, and the future of computing

00:04:13 – Innovation Under Pressure – How limitations create the best breakthroughs

00:05:46 – Mind Reading? – The wild world of telepathy research and what it means for biotech

00:07:45 – Quantum Strangeness – Exploring dimensions beyond what we can see

00:09:17 – Longevity Hacks – The Brian Johnson experiment: biohacking or billion-dollar placebo?

00:12:48 – Biomanufacturing is Booming – Why the future of production is biological

00:28:35 – PFAS Panic – 3M halts production, and microelectronics scrambles for solutions

00:30:53 – BioMADE’s Master Plan – How industry collaboration is making biomanufacturing real

00:36:56 – Government Meets Biotech – Bridging public and private sectors for impact

00:38:44 – The Bioeconomy is Here – What it means for industries beyond biotech

0:42:29 – Talk to Your Legislators – How to get policymakers to care about biotech

00:46:08 – The Hardest Part of Biomanufacturing – What innovators need to overcome

00:50:42 – Biomanufacturing’s Future – The biggest opportunities waiting to be unlocked

00:52:46 – Final Thoughts – Wrapping up lessons from the frontier of biotech

Links and Resources:

BioMADE

Homeworld Collective (Apply today!)

The Climate Biotech Podcast

DeepSeek Wipes $1 Trillion from Tech Share Prices

The Telepathy Tapes

Don't Die, The Man Who Wants to Live Forever

Rapamycin

General Probiotics

Antheia

Schmidt Sciences

Liberation Labs

Topics Covered: 

biomanufacturing, collaboration, public private partnerships, distributed biomanufacturing, longevity biotech, telepathy, tech 

Have a question or comment? Message us here:

Text or Call (804) 505-5553 

Instagram  / Twitter / LinkedIn / Youtube / Grow Everything

Email: [email protected]

Music by: Nihilore

Production by: Amplafy Media

Noah Helman, co-founder of Industrial Microbes, unpacks how his team is giving ethanol a glow-up as a renewable feedstock for creating advanced polymers and sustainable carbon fibers. With a decade of experience in the trenches of biomanufacturing, Noah discusses how they’re engineering microbes to work smarter, not harder, tackling the challenges of cost, scale, and environmental impact. From leveraging industrial partnerships to envisioning a future where waste becomes the ultimate raw material, Noah delivers sharp insights with a side of microbial magic, proving that biology is not just life—it’s a powerhouse of innovation.

Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?

Learn more at ⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠

Chapters:

Episode Links:

Topics Covered: Biomanufacturing, acrylic acid, acrylonitrile, carbon nanofibers, industrial microbes, biotech startups, spaceships, accelerators, synbio investments 

Have a question or comment? Message us here:

Text or Call (804) 505-5553

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Email: [email protected]

Music by: Nihilore

Production by: Amplafy Media

Erum and Karl have an incredible chat with Nick Edwards, the innovative mind behind Potato AI. Nick goes into the inspiration behind the platform's unique name, rooted in childhood curiosity and scientific wonder, and shares his journey from neuroscience research to building a groundbreaking tool aimed at accelerating scientific discovery. He explains how Potato tackles the overwhelming deluge of scientific literature and the reproducibility crisis using AI to structure and analyze data in transformative ways. With stories from his own career, a stint in consulting, and running his podcast "Once a Scientist," Nick discusses the future of AI, science, and collaboration. This episode has amazing insights into how technology is reshaping the very fabric of research.

Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?

Learn more at ⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠

Chapters:

Episode Links:

Topics Covered: Research, AI research assistant, AI Scientist, Biotech, Lab Automation, Reproducibility

Have a question or comment? Message us here:

Text or Call (804) 505-5553

⁠⁠⁠⁠Instagram⁠⁠⁠⁠  / ⁠⁠⁠⁠Twitter⁠⁠⁠⁠ / ⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠ / ⁠⁠⁠⁠Youtube⁠⁠⁠⁠ / ⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠

Email: [email protected]

Music by: Nihilore

Production by: Amplafy Media

Karl and Erum welcome Dr. Chris Mason. He’s a professor of genomics, physiology, and biophysics, as well as co-founder / COI of BiotiaNYC, Ursa Bio, and Onegevity. Chris will take you on a journey from the mysteries of space genomics to the hidden worlds of Earth's microbiomes. He discusses the intersection of advanced biology and space exploration, diving into his work with NASA’s twin study, the possibilities of planetary engineering, and his fascination with unknown DNA found even in urban subways. Chris also talks about how the convergence of ancient biological knowledge and cutting-edge technology could redefine humanity's future, both on Earth and beyond.

Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?

Learn more at ⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠

Chapters:

Episode Links:

Topics Covered: 

space genomics, urban microbiomes, dna discovery, planetary engineering, biotechnology trends, genetic engineering, synthetic biology tools, microbiome exploration

Have a question or comment? Message us here:

Text or Call (804) 505-5553

⁠⁠⁠Instagram⁠⁠⁠  / ⁠⁠⁠Twitter⁠⁠⁠ / ⁠⁠⁠LinkedIn⁠⁠⁠ / ⁠⁠⁠Youtube⁠⁠⁠ / ⁠⁠⁠Grow Everything⁠⁠⁠

Email: [email protected]

Music by: Nihilore

Production by: Amplafy Media

Karl and Erum give us a peek into their outlook for 2025, discussing biotech trends, the rise of decentralized science, and the convergence of AI with biology. They talk about the thawing of the "biotech winter," the potential risks of a new bird flu pandemic, and exciting innovations in quantum biology and drug discovery. Their conversation also touches on how waste can become a resource in biomanufacturing, the future of microbiome engineering, and the growing visibility of biotech in mainstream media. Tune in to hear Karl and Erum set the stage for an exciting year ahead in the world of biotech and beyond​.

Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?

Learn more at ⁠⁠www.messaginglab.com/groweverything⁠⁠

Chapters:

Episode Links:

Topics Covered: 

2025 outlook, decentralized science, quantum biology, longevity biotech, waste to value, waste as a resource, biomaterials, bioeducation, microbiome

Have a question or comment? Message us here:

Text or Call (804) 505-5553

⁠⁠Instagram⁠⁠  / ⁠⁠Twitter⁠⁠ / ⁠⁠LinkedIn⁠⁠ / ⁠⁠Youtube⁠⁠ / ⁠⁠Grow Everything⁠⁠

Email: [email protected]

Music by: Nihilore

Production by: Amplafy Media

Karl and Erum welcome Niklas Anzinger, the visionary founder of Vitalia, a decentralized city aimed at revolutionizing biotech and longevity. Niklas discusses the need for a more efficient drug development process, proposing a shift toward safety trials and medical reciprocity that could drastically shorten the time it takes to bring life-saving therapies to market. He talks about how Vitalia serves as a hub for biotech innovation, where companies can thrive outside traditional bureaucratic constraints. Niklas shares his ideas on medical freedom and the importance of allowing individuals to make informed choices about their health. He critiques the paternalistic nature of current healthcare systems, advocating for a more empowering approach that encourages personal responsibility and informed decision-making. Niklas believes that by creating a culture of innovation and flexibility, Vitalia can set new standards in healthcare, ultimately improving patient outcomes and accelerating scientific advancements. As Karl and Erum wrap up the episode, they express their excitement about the potential impact of Niklas’s vision—not just for Vitalia, but for the global landscape of biotech and longevity.

Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?

Learn more at ⁠www.messaginglab.com/groweverything⁠

Chapters:

Episode Links:

Topics Covered: 

longevity biotech, crypto, human enhancement, biohacking, network states, biopharma regulation, healthcare system, sickcare system, medical reciprocity, safety trials, patients right to choose, drug development, economics of science, quantum biology, aging biology, regulatory flexibility

Have a question or comment? Message us here:

Text or Call (804) 505-5553

⁠Instagram⁠  / ⁠Twitter⁠ / ⁠LinkedIn⁠ / ⁠Youtube⁠ / ⁠Grow Everything⁠

Email: [email protected]

Music by: Nihilore

Production by: Amplafy Media

Kevin Flyangolts joins Erum and Karl to talk about the evolving landscape of biosecurity. They discuss the rapid advancements in biotechnology, the growing accessibility of synthetic DNA, and the need for robust screening systems to ensure safety in the bioeconomy. Kevin shares knowledge from his software background, explaining how tools like those at Aclid Bio are bridging gaps in security, protecting against potential misuse, and setting the stage for future innovations in biotech. With reflections on government initiatives, industry collaboration, and the complexities of ethical biosecurity practices, this conversation showcases the urgent issues and exciting possibilities in the intersection of biology and technology.

Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?

Learn more at www.messaginglab.com/groweverything

Chapters:

Episode Links:

Topics Covered: 

biosecurity, DNA synthesis, BIOSECURE Act, computer science

Have a question or comment? Message us here:

Text or Call (804) 505-5553

Instagram  / Twitter / LinkedIn / Youtube / Grow Everything

Email: [email protected]

Music by: Nihilore

Production by: Amplafy Media

Andy Bass brings the ocean's glow to your hands, turning natural wonders like bioluminescent plankton into personal and immersive experiences. From creating the Dino Pet to designing ocean-bathing exhibits, Andy shares how biology can light up creativity, spark curiosity, and inspire the next generation of conservationists. It's a conversation about the intersection of nature, imagination, and the transformative power of "living art."

Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?

Learn more at⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠

Chapters:

Topics Covered: 

bioluminescence, biology, education, edutainment, entrepreneurship, biomaterials, cultivated food, mushrooms, mycelium, immersive experiences, gifts, dinoflagellates, plankton, oceans, deep sea, James Cameron, avatar

Episode Links:

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Text or Call (804) 505-5553

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Email: [email protected]

Music by: Nihilore

Production by: Amplafy Media

Karl and Erum are taking us deep into the intersection of biology, industry, and innovation with their guest, Jason Kakoyiannis. Jason is the founder of Bioscentric, advisor at Allonnia, and managing partner of Ferment! From starting his journey in the art world to leading the charge at Ferment, Jason shares how curiosity and the drive to solve complex problems led him to build a venture studio focused on market-driven biotech solutions. They discuss how biology can unlock sustainable answers to big challenges, like optimizing energy systems or creating eco-friendly alternatives in manufacturing. Along the way, Jason explains how his team finds the right problems to tackle and builds companies that merge creativity with real-world impact. It’s a fascinating look at how biotech is shaping our future—one bold idea at a time!

Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?

Learn more at⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠

Chapters:

Topics Covered: 

biotech funding, venture capital, venture studio, fermentation, startups, entrepreneurship, climate biotech.

Episode Links:

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Have a question or comment? Message us here:

Text or Call (804) 505-5553

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Email: [email protected]

Music by: Nihilore

Production by: Amplafy Media

Join Karl and Erum in this special Thanksgiving replay of Aaron Schacht’s episode as they revisit this fascinating conversation. Aaron is the CEO & Board Director of BiomEdit and he has a visionary approach to leveraging microbiome science and synthetic biology to tackle some of the biggest challenges in animal health. Whether it’s creating healthier livestock, addressing sustainability issues, or revolutionizing methane reduction in agriculture, this episode covers it all.

As Karl and Erum reflect on the year, they share what they’re thankful for before introducing Aaron’s episode. BiomEdit’s innovative strides, led by Aaron, let us in on the potential in animal agriculture and the power of biotechnology.

Please enjoy the full replay of Aaron Schacht’s episode—a perfect listen for a Thanksgiving break or any time you’re curious about how biology is shaping the future of our food systems and beyond!

Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?

Learn more at⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠

Chapters:

Topics Covered: biotech, biodesign, built environment, living environment, microbiome, research, discovery, brooklyn

Episode Links:

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Text or Call (804) 505-5553

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Email: [email protected]

Music by: Nihilore

Production by: Amplafy Media