Hack You

Hack You

By Vadim Fedotov, Mike ThurstonHealth & Fitness
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Hack You episodes

  • Peptide Bioregulators Explained: Sleep Better, Age Slower, Heal Faster

    Dean Henry returns for a conversation on all things bioregulators and breaks down why they're a different category of peptides altogether.


    Instead of signalling, they work like gene switches, going inside cells to switch genes on and off. He covers why they're taken in cycles, which specific ones address fertility, bladder issues, prostate health, and hormonal balance, and why Vadim's personal experience with sleep transformed his belief in the whole category.


    We also cover the stacking effect where combining bioregulators creates disproportionately better outcomes, real data from people getting pregnant after years of failed attempts, and why the evidence is stronger than most people realise.


    ↓ For all your peptide needs:


    UAE: https://uaepeptideresearch.com/


    Europe: https://dnlabresearch.com/peptide-bioregulators/


    00:00 Intro
    01:00 Introducing bioregulators
    07:13 How many bioregulators exist and the evidence behind them
    13:00 Why bioregulators are cycled instead of taken continuously
    18:35 Choosing personalised stacks based on individual health goals
    24:13 Male fertility, testosterone and prostate health
    30:55 Female fertility and the surprising impact on cycles
    36:51 Thyroid regulation and supporting digestive health
    42:13 Muscle recovery, joints and preparing for GLP-1s
    47:31 Parathyroid, respiratory health and the final bioregulators
    53:13 How to cycle bioregulators and choose quality products


    DISCLAIMER
    Nothing shared on this podcast is a substitute for professional medical guidance. Please consult a healthcare professional before making any health or lifestyle changes.


    Hack You Media
    → Instagram: https://www.instagram.com/hackyoumedia/
    → More from Hack You: https://hackyou.media/#aa19104a-abc1-4697-b0f5-0e81e47e60c5


    » Follow Vadim
    Instagram: https://www.instagram.com/vadim_bioniq/
    Bioniq: https://bioniqlab.com/


    » Follow Mike
    YouTube: https://www.youtube.com/MikeThurston
    Instagram: https://www.instagram.com/mikethurston/?hl=en
    First Things THRST: https://www.youtube.com/FirstThingsThrst


    » Follow Dean
    Instagram: https://www.instagram.com/dean.e.henry/?hl=en

    59 min
  • You're Using Creatine WRONG!: Here's The Protocol That Actually Works

    Dr Darren Candow has published over 1000 peer-reviewed studies on creatine, and he's found something surprising: the optimal dose depends entirely on what you're trying to achieve, and it's probably not what you've been taking.


    He breaks down why creatine monohydrate is still king despite flashy new forms, which dose actually works for muscle, bone, and brain, and why vegans respond so much better to supplementation.


    00:00 Introduction
    03:30 Historical perception shifts of creatine
    06:18 Personal stories and early experiences with creatine
    13:46 Types of creatine and supplement forms
    17:18 Monohydrate vs other creatine forms
    21:55 Dosing strategies and individual needs
    28:17 High doses for sleep deprivation recovery
    32:59 Effects of long-term high creatine use
    40:22 Does creatine cycling matter?
    45:07 Creatine's role in female health
    50:23 Supplements that synergise with creatine use
    54:02 Potential inhibitors of creatine's effects
    57:02 Exercise as an unmatched health tool


    DISCLAIMER
    Nothing shared on this podcast is a substitute for professional medical guidance. Please consult a healthcare professional before making any health or lifestyle changes.


    Hack You Media
    → Instagram: https://www.instagram.com/hackyoumedia/
    → More from Hack You: https://hackyou.media/#aa19104a-abc1-4697-b0f5-0e81e47e60c5


    » Follow Vadim
    Instagram: https://www.instagram.com/vadim_bioniq/
    Bioniq: https://bioniqlab.com/


    » Follow Mike
    YouTube: https://www.youtube.com/MikeThurston
    Instagram: https://www.instagram.com/mikethurston/?hl=en
    First Things THRST: https://www.youtube.com/FirstThingsThrst


    » Follow Darren
    Instagram: https://www.instagram.com/dr.darrencandow/?hl=en
    Website: https://www.uregina.ca/kinesiology-health-studies/directory/faculty/darrencandow.html

    1 hr 1 min
  • Heart Surgeon: Common Mistakes Destroying Your Heart, Muscle & Longevity

    Dr Jeremy London is a cardiovascular surgeon who breaks down why blood vessel health matters infinitely more than your heart rate, the ecosystem most cardiologists ignore, and why extreme endurance training and steroids create the exact same cardiac damage. Find out what you can actually change starting tomorrow and why VO2 max isn't the only number worth tracking.


    00:00 Introduction
    01:20 Broad definition of cardiovascular health beyond just the heart
    04:08 Importance of healthy blood vessels in the cardiovascular ecosystem
    07:23 Diet and exercise protocols for heart health
    16:02 Risks of excessive exercise and muscle growth
    20:11 Significance of VO2 Max in assessing cardiovascular efficiency
    24:35 The role and accuracy of HRV and wearables
    30:29 When to start focusing on heart health and personal anecdote
    35:00 Changing perceptions of atherosclerosis as a universal condition
    42:50 Personal story of ignoring heart attack symptoms
    49:50 Medications and lifestyle changes to manage APOB levels
    57:21 Balancing lifestyle choices with cardiovascular risk factors
    1:04:30 Impact of family history and lifestyle on heart health
    1:09:26 Effects of caffeine and popular cardiovascular myths
    1:12:11 Rapid-fire questions about heart health misconceptions


    DISCLAIMER
    Nothing shared on this podcast is a substitute for professional medical guidance. Please consult a healthcare professional before making any health or lifestyle changes.


    Hack You Media
    → Instagram: https://www.instagram.com/hackyoumedia/
    → More from Hack You: https://hackyou.media/#aa19104a-abc1-4697-b0f5-0e81e47e60c5


    » Follow Vadim
    Instagram: https://www.instagram.com/vadim_bioniq/
    Bioniq: https://bioniqlab.com/


    » Follow Mike
    YouTube: https://www.youtube.com/MikeThurston
    Instagram: https://www.instagram.com/mikethurston/?hl=en
    First Things THRST: https://www.youtube.com/FirstThingsThrst


    » Follow Jeremy
    Instagram - https://www.instagram.com/drjeremylondon/
    Newsletter - https://www.drjeremylondon.com/newsletter

    1 hr 14 min
  • Why Most Men Can't Fix Their Energy, Fat Loss Or Focus (The Real Reason)

    Nathan Carvalho calls himself a human optimisation architect because most people are getting the sequence wrong. He spends weeks connecting the dots between your gut doctor, thyroid doctor, trainer, and nutritionist - people who don't talk to each other but should.


    He breaks down why people waste thousands on SS31 and Methylene Blue while missing basic B vitamins and magnesium, how mitochondria are the foundation everything else builds on, and why the body has a specific order of operations most people ignore. Also covers what the first phase of optimisation actually looks like and why it feels terrible before it feels amazing.


    00:00 Introduction
    05:38 Personal journey and holistic view on human biology
    12:01 Major differences between research and real-world application
    16:14 The importance of mitochondria in physical goals
    24:33 Myths and truths regarding T3 and body function
    33:15 T3's comprehensive impact on body performance
    41:24 Interaction between testosterone, growth hormone, and T3
    45:47 Importance of insulin sensitivity in hormone therapy
    50:49 Strategic use of peptides for muscle building and recovery
    54:45 Quick-fire questions: trends, overrated peptides, daily habits
    57:25 Final thoughts on the significance of circadian rhythms and light exposure
    58:54 Closing remarks and where to find more information


    DISCLAIMER
    Nothing shared on this podcast is a substitute for professional medical guidance. Please consult a healthcare professional before making any health or lifestyle changes.


    Hack You Media
    → Instagram: https://www.instagram.com/hackyoumedia/
    → More from Hack You: https://hackyou.media/#aa19104a-abc1-4697-b0f5-0e81e47e60c5


    » Follow Vadim «
    Instagram: https://www.instagram.com/vadim_bioniq/
    Bioniq: https://bioniqlab.com/


    » Follow Nathan«
    Instagram: https://www.instagram.com/optimalnathan/
    Website: https://theoptimizationlab.cc/bio

    1 hr
  • The Keto Expert: Improve Fat Loss & Muscle Growth By Eating MORE (Not Less)

    Latt Mansor has a PhD in physiology from Oxford studying metabolic flexibility, and he discovered something uncomfortable about himself: he was skinny fat at 26% body fat and nothing he did worked until he did the opposite.


    He breaks down why 90% of Americans are metabolically inflexible, what exogenous ketones actually do versus what they don't, and why the solution isn't always less, sometimes your body needs more to recognise it's not starving.


    00:00 Introduction
    04:41 Personal motivation and research journey
    08:57 Exploring ketones and ketosis basics
    12:09 Measuring ketones: different methods explained
    16:02 Importance of metabolic flexibility
    19:21 Skinny fat and metabolic inflexibility overview
    23:14 Benefits of exogenous ketones
    29:27 Surprising effects of ketones on sleep
    36:02 Debunking health myths and misinformation
    41:14 Personalised diet and wellness strategies


    DISCLAIMER
    Nothing shared on this podcast is a substitute for professional medical guidance. Please consult a healthcare professional before making any health or lifestyle changes.


    Hack You Media
    → Instagram: https://www.instagram.com/hackyoumedia/
    → More from Hack You: https://hackyou.media/#aa19104a-abc1-4697-b0f5-0e81e47e60c5


    » Follow Vadim «
    Instagram: https://www.instagram.com/vadim_bioniq/
    Bioniq: https://bioniqlab.com/


    » Follow Latt«
    Instagram: https://www.instagram.com/lattmansor/?hl=en
    Website: https://linktr.ee/lattmansor

    44 min
  • I Took Too Many Peptides And Ended Up In The ICU (Avoid This) | Anthony Castore

    » Produced by Hack You Media: pioneering a new category of content at the intersection of health performance, entrepreneurship & cognitive optimisation.
    Instagram: https://www.instagram.com/hackyoumedia/
    Website: https://hackyou.media/


    Anthony Castore knows peptides better than almost anyone alive, but stacking them without the right foundation nearly killed him. He spent five days in ICU with a breathing tube after trying to optimise himself into oblivion before speaking at Peptide World Congress.


    He breaks down the pyramid model most people build upside down, why phase shifts in your cells matter more than which GLP you pick, and how damaged mitochondria can lock you into a metabolic state where nothing works. For people serious about using peptides intelligently.


    00:00 Introduction
    05:28 Anthony's personal health scare and lesson
    12:08 Starting weight loss journey with peptides
    21:41 Understanding peptide dosage and timelines
    28:47 Addressing hunger and food noise with peptides
    33:56 Two peptides and supplements for fat loss
    39:50 Exploring ketone monoester benefits
    45:09 Looksmaxxing: Peptides for aesthetic improvements
    52:11 Peptide use in competitive and bodybuilding contexts
    59:08 "Natural" status with peptides
    1:02:24 Amplifying your body's natural capabilities with peptides
    1:10:42 Health trends and misconceptions
    1:12:01 Importance of journaling for mental clarity
    1:14:31 Where to find more info from Anthony Castore


    DISCLAIMER
    Nothing shared on this podcast is a substitute for professional medical guidance. Please consult a healthcare professional before making any health or lifestyle changes.


    Hack You Media
    → Instagram: https://www.instagram.com/hackyoumedia/
    → More from Hack You: https://hackyou.media/#aa19104a-abc1-4697-b0f5-0e81e47e60c5


    » Follow Vadim «
    Instagram: https://www.instagram.com/vadim_bioniq/
    Bioniq: https://bioniqlab.com/


    » Follow Mike«
    YouTube: https://www.youtube.com/MikeThurston
    Instagram: https://www.instagram.com/mikethurston/?hl=en
    First Things THRST: https://www.youtube.com/FirstThingsThrst


    » Follow Anthony«
    Instagram: https://www.instagram.com/anthonycastore/
    Website: https://www.castoremethod.com/

    1 hr 17 min
  • How To Lose Visceral Fat So Fast It Feels Like Cheating | Dr Sean O'Mara


    Dr Sean O'Mara spent years studying visceral fat through MRI scans and discovered the uncomfortable truth: most people have zero awareness they're filled with disease because it doesn't show on the outside. Distance runners look shredded, but their internal scans reveal something shocking.


    He breaks down why selection pressure (what actually keeps you alive) got replaced by selection pleasure, and why the three main drivers most people focus on miss the synergy that actually works.


    00:00 Introduction
    01:02 Dr Sean discusses law and medicine career journey
    06:30 Overcoming personal health issues through lifestyle changes
    12:00 Realisation of the impact of lifestyle on health
    17:18 Specialising in visceral fat due to its health impact
    22:40 Discovering ectopic fat in muscles during scans
    27:46 Role of diet and lifestyle in reducing visceral fat
    31:53 Sprinting vs. distance running in fat reduction
    35:00 Tailoring sprinting and dietary approaches for individuals
    39:52 MRI insights into muscle mass and fat
    43:09 Importance of fermented foods for gut health
    50:01 Exploring effects of microbiome on visceral fat
    55:59 MRI scans and gut microbiome assessment
    1:00:51 Dr Sean's daily diet and lifestyle habits
    1:06:30 Final advice: Stop processed foods, start fermented foods


    DISCLAIMER
    Nothing shared on this podcast is a substitute for professional medical guidance. Please consult a healthcare professional before making any health or lifestyle changes.


    Hack You Media
    → Instagram: https://www.instagram.com/hackyoumedia/
    → More from Hack You: https://hackyou.media/#aa19104a-abc1-4697-b0f5-0e81e47e60c5


    » Follow Vadim «
    Instagram: https://www.instagram.com/vadim_bioniq/
    Bioniq: https://bioniqlab.com/


    » Follow Mike«
    YouTube: https://www.youtube.com/MikeThurston
    Instagram: https://www.instagram.com/mikethurston/?hl=en
    First Things THRST: https://www.youtube.com/FirstThingsThrst


    » Follow Dr Sean«
    Instagram: https://www.instagram.com/drseanomara/?hl=en
    Website: https://drseanomara.com/

    1 hr 5 min
  • 31 Years Old But Biologically In My Teens (Here's Exactly How)

    » Produced by Hack You Media: pioneering a new category of content at the intersection of health performance, entrepreneurship & cognitive optimisation.
    Instagram: https://www.instagram.com/hackyoumedia/
    Website: https://hackyou.media/


    Siim Land reversed his biological age from 31 to low double digits, but he's not obsessing over the metrics most people focus on.


    He explains which genes actually matter for longevity, why blood markers tell a better story than genetics, and the surprising way health anxiety is sabotaging your results. Also covers why measuring everything can create the problem you're trying to avoid.


    00:00 Introduction
    04:06 Genetics vs. environment in determining longevity risks
    10:24 Importance of regular blood work in preventive health
    14:05 Misconceptions in longevity and the role of genetic therapies
    18:20 Health anxiety and its impact on mental and physical health
    21:44 Bryan Johnson's lifestyle and discovery of autoimmune issues
    28:19 Calorie intake vs. quality of food for health outcomes
    33:08 Impacts of meal timing and fasting on lifespan
    39:43 Top recommended supplements and their significance
    44:24 Discussion on glycine supplementation and dosage
    48:52 Overrated supplements in the longevity space
    52:40 Critique of popular health trends like the Italian lifestyle
    55:05 Everyday habits Siim doesn't obsess over
    57:10 Siim's recommended health hack for overall improvements


    DISCLAIMER
    Nothing shared on this podcast is a substitute for professional medical guidance. Please consult a healthcare professional before making any health or lifestyle changes.


    Hack You Media
    → Instagram: https://www.instagram.com/hackyoumedia/
    → More from Hack You: https://hackyou.media/#aa19104a-abc1-4697-b0f5-0e81e47e60c5


    » Follow Vadim «
    Instagram: https://www.instagram.com/vadim_bioniq/
    Bioniq: https://bioniqlab.com/


    » Follow Mike«
    YouTube: https://www.youtube.com/MikeThurston
    Instagram: https://www.instagram.com/mikethurston/?hl=en
    First Things THRST: https://www.youtube.com/FirstThingsThrst


    » Follow Siim«
    Instagram: https://www.instagram.com/siimland/?hl=en
    Website: https://www.skool.com/top1health/

    59 min
  • Debunking The Biggest Fitness Industry Myths (and what actually works) Stan Efferding

    » Produced by Hack You Media: pioneering a new category of content at the intersection of health performance, entrepreneurship & cognitive optimisation.
    Instagram: https://www.instagram.com/hackyoumedia/
    Website: https://hackyou.media/


    Stan Efferding spent decades coaching weight loss clients, and the science is clear: your body actively resists fat loss by increasing hunger hormones, making it a biological problem, not a willpower issue.


    The Vertical Diet is systematic, calorie deficit, adequate protein for hunger control, minimum healthy fats, and then carbs chosen for satiety. Boiled potatoes beat everything for keeping you full, especially if you cool them overnight to create resistant starch that feeds your gut. Training matters infinitely more than diet optimisation, and most people skip it entirely. Only creatine and caffeine are worth supplementing. Internet obsession with glucose spikes and CGM monitoring is noise, distracting from the actual problem: hyper-palatable, cheap foods engineered to make you overeat. Fix your environment and hunger first, not the details.


    00:00 Intro
    03:12 Stan's background as a skinny kid turned professional bodybuilder
    11:20 Deficiencies hidden in restrictive diets and the female athlete triad
    14:24 Red meat, dairy and the 1.6g protein consensus broken down
    19:30 White rice as an energy tool
    27:48 White rice vs brown rice
    33:48 Satiety index potato swaps and practical tools to beat hunger
    37:47 Pre-workout nutrition and why training intensity beats everything else
    43:00 Caffeine, perceived effort and the psychology of pushing past failure
    48:21 Overrated trends, seed oils and bro science debunked
    53:00 How misinformation spreads and the value of staying academically honest
    01:01:38 The Shark Tank experience
    01:08:53 Life in American Samoa and running an online business
    01:10:41 The one hack: sleep apnea resolution


    DISCLAIMER
    Nothing shared on this podcast is a substitute for professional medical guidance. Please consult a healthcare professional before making any health or lifestyle changes.


    Hack You Media
    → Instagram: https://www.instagram.com/hackyoumedia/
    → More from Hack You: https://hackyou.media/#aa19104a-abc1-4697-b0f5-0e81e47e60c5


    » Follow Vadim «
    Instagram: https://www.instagram.com/vadim_bioniq/
    Bioniq: https://bioniqlab.com/


    » Follow Mike«
    YouTube: YouTube.com/@mikethurston
    Instagram: https://www.instagram.com/mikethurston/?hl=en
    First Things THRST: YouTube.com/@firstthingsthrst


    » Follow Stan«
    Instagram: https://www.instagram.com/stanefferding/?hl=en
    Website: https://stanefferding.com/

    1 hr 13 min
  • I've Discovered The Best Supplement Stack For Energy, Focus & Longevity

    » Produced by Hack You Media: pioneering a new category of content at the intersection of health performance, entrepreneurship & cognitive optimisation.
    Instagram: https://www.instagram.com/hackyoumedia/
    Website: https://hackyou.media/


    The mitochondrial stack that changed bodybuilding, and why brain damage from compounds can't be undone.


    Dean created a stack (Motzi, SLUPP, Methylene Blue) after fixing his gut issues and realising optimised metabolism meant he never needed to starve during prep, calories in/calories out ignores actual metabolic efficiency. Most people don't realise compounds that spike dopamine permanently fry your brain's reward system, leaving guys with normal testosterone but zero libido because their dopamine receptors are damaged. Teenagers now skip the basics and jump straight to peptides, thinking it shortens years of work, but that's where irreversible harm happens.


    00:00 Introduction
    01:28 Starting from scratch and moving to a new city
    04:00 Leaving a secure job for passion
    08:30 Personal health challenges and breakthroughs
    12:05 Creating an energy-boosting supplement stack
    17:20 Psychological impact of extreme dieting in bodybuilding
    22:30 Balancing nutrient intake for optimal brain function
    26:40 Addressing dopamine and libido post-steroid cycles
    31:00 The rise and influence of peptide use in fitness
    35:10 Impact of social media on health trends and youth
    40:10 Longevity vs muscle mass: navigating trade-offs
    45:20 The complex nature of obesity beyond diet
    48:50 Utilities and drawbacks of GLP-1 usage in weight loss
    54:30 Hair loss treatments: options and myths
    58:30 Testosterone replacement therapy: next steps and pitfalls
    1:04:00 The interplay of mental health and supplements
    1:08:45 Managing oxidative stress for better health
    1:13:20 Developing a balanced approach: gains vs health risks


    DISCLAIMER
    Nothing shared on this podcast is a substitute for professional medical guidance. Please consult a healthcare professional before making any health or lifestyle changes.


    Hack You Media
    → Instagram: https://www.instagram.com/hackyoumedia/
    → More from Hack You: https://hackyou.media/#aa19104a-abc1-4697-b0f5-0e81e47e60c5


    » Follow Vadim «
    Instagram: https://www.instagram.com/vadim_bioniq/
    Bioniq: https://bioniqlab.com/


    » Follow Mike«
    YouTube: YouTube.com/MikeThurston
    Instagram: https://www.instagram.com/mikethurston/?hl=en
    First Things THRST: YouTube.com/FirstThingsThrst


    » Follow Dean«
    Instagram: https://www.instagram.com/deanstm/?hl=en
    Website: https://linktr.ee/deanstm

    1 hr 23 min

About Hack You

From the publisher's feed

Co-hosted by Mike Thurston and Vadim Fedotov, Hack You is a space for real conversations with world-class experts on what you can do to optimise your health and performance.