What does it take to make a great run-based game? Tight combat, of course. A variety of mix-and-match abilities that interact in interesting ways, certainly. Procedurally generated levels are nice. Progression and other systems that help each new run stay fun for hours and hours are definitely essential. Hades, an isometric beat-em-up from developer Supergiant Games, offers all these things even in its early access launch state, and sets its sights even higher.