Five risk factors explain 50 per cent of cardiovascular risk at age 50, according to a new study. 

Addressing those risk factors can add years to your life, even if you address them in middle age. 

Also, the UK demonstrates a cutting edge IVF technique is effective at avoiding mitchondrial disease. 

ADHD treatment has real world positives, but the effects are lessening as more people get diagnosed. 

And an update on how RSV vaccination in pregnant women is going, five months into the program.  

The human exposome is the environmental equivalent of the human genome, and there's a project in the works to map it. 

It's a huge project that needs to take into account our lifestyles, cultures, economics and politics. Essentially, everything but our genome. 

Also, a concerning disparity between Indigenous and non-Indigenous Australians when it comes to kidney transplants. 

And a small risk comes to light in relation to GLP-1s used for diabetes and weight loss. 

References

• Guidance on medicinal cannabis prescribing targets unsafe practice - AHPRA
• GLP-1 Drugs Linked to Higher Risk of Age-Related Macular Degeneration
• Am I on the list? Clinician‐reported factors for kidney transplantation non‐waitlisting among Aboriginal and Torres Strait Islander people with kidney failure: a cross‐sectional study
• The Human Exposome Project
• Generation Cancer - 4Corners
• Mapping the chemical complexity of plastics - Nature

Immunotherapy uses the body's immune system to fight cancer. In blood cancer, a revolutionary t-cell therapy has cured patients and could show promise in solid tumours. 

In bladder cancer, the tuberculosis vaccine is infused to treat non-invasive cancer. However a shortage of BCG means researchers are having to test out other methods. 

Also, is Australia on the front foot when it comes to type 2 diabetes treatment? And what does copper in the brain have to do with Parkinson's disease?

In the burgeoning field of artificial intelligence, it can sometimes feel like the answer to everything is right around the corner. 

A dog owner is testing this with the help of super-computing, to try and find another treatment for his dog's cancer. 

Also, the national lung cancer screening program is about to begin. Who is eligible, and is the healthcare system prepared?

And with syphilis cases rising in the community, there are implications for expectant mothers. 

Hyenas and vultures play a role in driving down the risk of disease outbreaks, but their decline due to human behaviour is putting our health in danger.

Also, we discuss Lifeblood's changes which bring down some of the barriers facing gay and bisexual men, and transgender women, who'd like to donate blood or plasma. 

Pain education could help people with osteoarthritis get the most out of exercise programs — and even walk the Camino. 

Plus there's a push to extend genetic carrier screening to cover dozens more conditions. 

There are concerns people are getting their hands on medicinal cannabis to treat conditions where there's very little evidence of benefit — and the possibility of harm. 

Also, why weight loss drugs could improve treatment for people with schizophrenia. The full breadth of corporate ownership of radiology clinics is revealed. 

And what questions need to be asked with IVF in the spotlight, as Monash IVF deals with the fallout from a second bungled embryo transfer.

References:

• Medicinal cannabis prescribing practices under scrutiny after scripts issued 'every 4 minutes' - ABC News
• ‘Infuriating and dangerous’: Psychiatrist tries and fails to speak with his patients’ medicinal cannabis prescribers - AusDoc.
• Efficacy and safety of semaglutide versus placebo for people with schizophrenia on clozapine with obesity (COaST): a phase 2, multi-centre, participant and investigator- blinded, randomised controlled trial in Australia
• Corporatisation and ownership concentration in diagnostic imaging: an audit of Australian practices

A structured exercise program has increased survival in people with colon cancer after they've undergone surgery and chemotherapy. 

Also, a common genetic variant could double the risk of dementia in men — if they receive two doses of the mutation. 

We provide an update on the flu, COVID and RSV circulating the community.

And a study bringing together millions of lab tests has found is take a lot longer for the body to bounce back from pregnancy than commonly thought. 

References:

• Measles Seroprevalence in Infants Under 9 Months of Age in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis
• Gene–Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies
• Structured Exercise after Adjuvant Chemotherapy for Colon Cancer - NEJM 
• Haemochromatosis Genotypes and Incident Dementia in a Prospective Study of Older Adults
• Pregnancy and postpartum dynamics revealed by millions of lab tests - ScienceAdvances

al issues from social, scientific and political points of view.

Our cognitive ability changes throughout our lives, but what happens when we're young can determine our intelligence in adulthood — especially if we don't do anything to bolster it.  

Also, NSW follows other states in allowing GPs and diagnose and treat ADHD. There are updated guidelines for the treatment of osteoporosis. 

And when you go into remission from cancer, you usually undergo regular tests to make sure it hasn't returned. But does the evidence support this is beneficial, or simply a cause for anxiety?

If you've come across ads of Norman pushing a product for you to buy — no you haven't. 

These ads are actually deepfake scams using an AI Norman to sell unproven supplements. 

Also, why a new Alzheimer's drug coming onto the market might not become cheap enough for most people to take. 

A breakthrough in gene-editing could push us closer to a future full of CRISPR treatments. And why eight hours a night might not be the magic number for sleep. 

Gut health is more complicated than social media influencers might have you believe. 

It can be impacted by diet, exercise, the medications you take, the colds you catch. And any one of these factors can lead to irritable bowel syndrome. 

Also, an overlooked allergy that starts with a tick bite. And the barriers people face who are suffering iron deficiency and its often overwhelming symptoms.