He studied medicine and began to rise rapidly in the medical profession. His life changed when he had a series of deep experiences of God which gave him a love and zeal for Christ. Soon, despite having the most promising of medical careers before him, Lloyd-Jones felt called to preach. In 1927, without any formal theological training, he left medicine and, taking a massive salary cut, went with his wife Bethan to pastor a struggling church in Port Talbot, one of the poorest areas of South Wales.