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Hit a wall 

means to reach a point where you can’t continue — usually because you’re tired, out of ideas, or emotionally exhausted.
 It’s like running full-speed into an invisible wall that stops you in your tracks.

Examples

1- During the third week of my new job, I hit a wall — the pressure and lack of sleep just got to me.

2- He was trying to stay positive after the breakup, but one night he just hit a wall and couldn’t hold back the tears.