All three suffered during the reign of Diocletian. Though born in three different places, the three were found to be Christians at Pompeiopolis in Cilicia, arrested together, and brought before the Governor, Numerian Maximus. Tarachus was sixty-five years old at the time of his arrest, but his captors showed no respect for his age, tormenting him as cruelly as the others. All three immediately and boldly confessed their faith, and were put to many vicious tortures, during which Probus said to Maximus, 'This bloodshed is oil and perfume for me to anoint myself with joy for further contests.' At one point the persecutors forcibly stuffed Andronicus' mouth with meat and wine that had been offered to idols, thinking that in doing so they were winning a victory. Andronicus only mocked them, explaining that only wilful apostasy brings defeat to a Christian.

Finally, Maximus ordered them taken to the theater and thrown to wild beasts for the entertainment of the people. Though the beasts had just torn others to pieces, they would not touch the holy martyrs, but played and fawned around them: A ferocious bear licked their wounds, and a lioness played affectionately around Tarachus. Seeing this, many in the crowd believed in Christ and denounced the Governor. The furious Maximus ordered his soldiers to enter the arena and cut the three to pieces. Three Christians who had witnessed the spectacle came by night to retrieve their bodies, but were unable to distinguish the martyrs' relics amid the general carnage. When they prayed for divine aid, three lights appeared above the bodies of the three holy ones, and they were given honorable burial in a mountain cave.