The Hematologist

How FLT3-ITDs & NPM1 Insertions Maneuver Into AML Using Lymphoid Enzyme TdT With Drs. Kim & Borrow


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In this podcast, Contributing Editor Dr. Annette Kim has a conversation with Dr. Julian Borrow. They discuss Dr. Kim's Diffusion article from the March/April 2020 issue of The Hematologist. The article titled, "How FLT3-ITDs and NPM1 Insertions Maneuver Into AML Using the Lymphoid Enzyme TdT to Initiate Replication Slippage," discusses the prominent role of TdT in the generation of FLT3-ITD and NPM1c mutations in acute myeloid leukemia (AML). You can find her (and co-author, Dr. John LaMacchia's) Diffusion article online at www.hematology.org/Thehematologist/Diffusion/10277.aspx.
Music: “Jellyfish in Space” Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 creativecommons.org/licenses/by/3.0/
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