Featuring perspectives from Dr Adam M Brufsky and Dr Kevin Kalinsky, including the following topics:

• Introduction (0:00)
• Current and Future Role of TROP2-Directed Antibody-Drug Conjugates in Therapy for Triple-Negative Breast Cancer (TNBC) — Dr Brufsky (5:08)
• Established Treatment Paradigm for Localized and Metastatic TNBC — Dr Kalinsky (35:20)

CME information and select publications

Featuring an interview with Prof Bernd Kasper, including the following topics:

• Case: A woman in her early 30s develops a progressing desmoid tumor in her abdomen during pregnancy(0:00)
• Case: A woman in her late 30s with a painful small desmoid tumor in her rectus abdominus undergoes cryoablation (8:04)
• Case: A woman in her late teens with recurrent desmoid tumors in her right thigh undergoes multiple resections (13:58)
• Case: A woman in her mid 70s has a desmoid tumor causing erosion in her scapular region (17:19)

CME information and select publications

Featuring perspectives from Dr Deborah K Armstrong and Dr David M O'Malley, including the following topics:

• Introduction (0:00)
• PARP Inhibitors and Strategies Targeting Folate Receptor Alpha in Advanced Ovarian Cancer — Dr Armstrong (4:37)
• Other Novel Agents and Strategies for the Treatment of Advanced Ovarian Cancer — Dr O'Malley (35:18)

CME information and select publications

Featuring perspectives from Dr Yelena Y Janjigian and Dr Samuel J Klempner, including the following topics:

• Introduction (0:00)
• Role of Anti-PD-1/PD-L1- and CLDN18.2-Directed Antibodies in the Management of Gastroesophageal Cancers — Dr Klempner (5:52)
• Management of HER2-Positive Gastroesophageal Cancers — Dr Janjigian (28:20)

CME information and select publications

Featuring perspectives from Dr Hans Lee and Dr Noopur Raje, including the following topics:

• Introduction (0:00)
• Integrating Chimeric Antigen Receptor T-Cell Therapy and Bispecific Antibodies into the Management of Relapsed/Refractory Multiple Myeloma (R/R MM) — Dr Raje (4:30)
• Antibody-Drug Conjugates and Other Emerging Therapies for R/R MM — Dr Lee (28:33)

CME information and select publications

Featuring a slide presentation and related discussion from Prof Martin Reck, including the following topics:

• Overview of small cell lung cancer (SCLC) (0:00)
• First-line chemoimmunotherapy for extensive-stage SCLC (ES-SCLC) (3:50)
• Lurbinectedin as first-line maintenance therapy for ES-SCLC (12:36)
• Case: A man in his early 60s with ES-SCLC receives first-line atezolizumab/carboplatin/etoposide followed by maintenance lurbinectedin/atezolizumab (18:46)
• Case: A woman in her mid 70s with ES-SCLC experiences a strong response to first-line chemoimmunotherapy and maintenance lurbinectedin/atezolizumab (21:21)

CME information and select publications

Featuring an interview with Prof Martin Reck, including the following topics:

• Case: A woman in her mid 70s with extensive-stage small cell lung cancer (ES-SCLC) experiences a strong response to first-line chemoimmunotherapy and maintenance lurbinectedin/atezolizumab (0:00)
• Biology of small cell lung cancer and pharmacodynamics of systemic treatment (3:25)
• Considerations with maintenance therapy for ES-SCLC (9:31)
• Considerations with immunotherapy for ES-SCLC (13:12)
• Curability of SCLC with systemic therapy (15:17)
• Data with chemoimmunotherapy for patients with poor performance status (25:55)
• Future developments in therapy for SCLC (30:11)
• Rapid fire: Small Cell 101 (35:45)

CME information and select publications

Featuring perspectives from Dr Terence Friedlander and Dr Daniel P Petrylak, including the following topics:

• Introduction (0:00)
• Role of Immunotherapeutic Strategies in the Management of Nonmetastatic Urothelial Bladder Cancer (UBC); Emerging Utility of Circulating Tumor DNA Evaluation — Dr Friedlander (3:53)
• Other Novel Agents and Strategies for Nonmetastatic and Metastatic UBC — Dr Petrylak (26:41)

CME information and select publications

Featuring perspectives from Dr Joyce F Liu, Dr David M O'Malley and Dr Brian M Slomovitz, moderated by Dr O'Malley, including the following topics:

• Introduction (0:00)
• Strategies to Identify Patients with HER2-Positive Gynecologic Cancers — Dr Liu (2:52)
• Available Data with and Practical Application of HER2-Targeted Therapy in Advanced Gynecologic Cancers — Dr Slomovitz (25:16)
• Identification and Management of Adverse Events with Trastuzumab Deruxtecan — Dr O'Malley (1:00:31)

CME information and select publications

Featuring perspectives from Dr John N Allan and Dr Adam Kittai, including the following topics:

• Introduction (0:00)
• Current Management of Newly Diagnosed Chronic Lymphocytic Leukemia — Dr Allan (8:47)
• Noncovalent Bruton Tyrosine Kinase Inhibitors and Other Novel Strategies — Dr Kittai (38:14)

CME information and select publications