The efficacy of the gold standard for bipolar treatment as been reported to be as high as 80%. But in the real world, that number is more like 25%. Why the disparity? What can we do for our treatment resistant bipolar patients? Dr. Robert Post professor of psychiatry at George Washington University School of Medicine and Penn State College of Medicine and head of the Bipolar Collaborative Network joins host Dr. Leslie Lundt to give us the latest on how to diagnose and treat these patients.