IJGC Podcast

By BMJ GroupMedicine Health & Fitness

IJGC Podcast episodes

January 25, 2023 Prolonged Maintenance with Bevacizumab (BOOST Trial) with Jacobus Pfisterer and Philipp Harter
In this episode of the IJGC podcast, Editor-in-Chief, Dr. Pedro Ramirez, is joined by Professors Jacobus Pfisterer and Philipp Harter to discuss prolonged maintenance with bevacizumab. Prof. Philipp Harter is the director of the Department of Gynecology & Gynecologic Oncology at Kliniken Essen-Mitte in Essen, Germany and the chair of the AGO Study Group. Prof. Jacobus Pfisterer is Director of the Gynecologic Oncology Center in Kiel Germany and former chair of the AGO Study Group.
Highlights:
- 30-month bevacizumb maintenance does not improve progression-free survival nor overall survival in advanced ovarian cancer.
- 30-month bevacizumb maintenance is associated with more adverse events compared to 15 months.
- 15-month bevacizumb maintenance remains standard of care.
33 min
January 18, 2023 Precursors of Ovarian Cancer with Elvio Silva
In this episode of the IJGC podcast, Editor-in-Chief, Dr. Pedro Ramirez, is joined by Dr. Elvio Silva to discuss precursors of ovarian cancer. Dr. Silva received a medical degree from the Universidad de La Plata and has been a faculty member at M.D. Anderson Cancer Center since 1980. He had pathology residences in Buenos Aires, Argentina, and University of Toronto, Canada and is the former President of the International Society of Gynecological Pathologists.
Highlights:
- Most ovarian serous tumors originate in the ovarian stroma.
- Ovarian serous tumors originate in the epithelium of inclusion cysts or in epithelial areas that appear in the stroma due to mesenchymal-epithelial transition.
- Mesenchymal-epithelial transition in serous tumors mimics the development of the Mullerian duct from the celomic mesenchyma.
39 min
January 11, 2023 Hormone Replacement Therapy after Cervical Cancer with Jason Wright
In this episode of the IJGC podcast, Editor-in-Chief, Dr. Pedro Ramirez, is joined by Dr. Jason Wright to discuss hormone replacement therapy after cervical cancer. Dr. Wright is the Sol Goldman Associate Professor and Chief of the Division of Gynecologic Oncology at Columbia University.
Highlights:
- Among cervical cancer patients - Black patients were significantly less likely to receive estrogen replacement therapy than White patients.
26 min
January 06, 2023 Novel High-Grade Serous Ovarian Morphologic Classification with Anil K. Sood
In this episode of the IJGC podcast, Editor-in-Chief, Dr. Pedro Ramirez, is joined by Dr. Anil K. Sood to discuss novel high-grade serous ovarian morphologic classification. Dr. Sood is a Professor in the Department of Gynecologic Oncology and Reproductive Medicine at the UT MD Anderson Cancer Center. He is Co-Director of the multi-disciplinary Blanton-Davis Ovarian Cancer Research Program and co-leads the Ovarian Cancer Moonshot Program. He is an elected member of the American Society for Clinical Investigation (ASCI), the Association of American Physicians (AAP), and the National Academy of Medicine (NAM).
Highlights:
- High grade serous ovarian cancer (HGSOC) could be classified into two gross morphologic subtypes.
- Type I and type II morphologic subtypes differed with respect to clinical outcomes.
- The two morphologic subtypes also differed with regard to transcriptomic, proteomic, and metabolomic profiles.
37 min
December 30, 2022 “Impact of Transfusions on Outcomes in Ovarian Cancer” with Lauren Prescott
In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez is joined by Dr. Lauren Prescott to discuss the impact of transfusions on outcomes in ovarian cancer. Dr. Prescott received her undergraduate degree from Georgetown University and went on study at the National Institutes of Health for two years. She then completed medical school at Georgetown University, residency in Obstetrics and Gynecology at Dartmouth Hitchcock Medical Center, and fellowship in Gynecologic Oncology at MD Anderson Cancer Center. She has been at Vanderbilt University since 2017. Dr. Prescott's research interests include measuring and evaluating surgical and oncologic outcomes and improving the quality of health care delivery through implementation of evidence-based medicine. Dr. Prescott leads the Vanderbilt Enhanced Recovery After Surgery Program for patients undergoing gynecologic surgery.
Highlights:
- Perioperative blood transfusions in ovarian cancer is common with 53% of patients in our study having received a transfusion
- Blood transfusions were not associated with negative impact on progression-free survival or overall survival
- However, blood transfusions were associated with increased peri-operative morbidity without improvements in quality of life
20 min
December 14, 2022 Revisited: ”Featured Mentor’s Podcast: Christina Fotopoulou”
In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez, is joined by Professor Christina Fotopoulou. Professor Fotopoulou works at the Department of Surgery and Cancer at Imperial College London, UK. She is an elected ESGO council member and Chair of the ESGO guidelines committee.
Highlights:
- Early support from mentors and "giants" in the field, national and international networking and early focusing/specialization in the field of interest are keys to success
- Try to turn your weaknesses and failures to learning points and opportunities to make you stronger
- Hard work, kindness and caring for patients, team spirit, professionalism and dedication are the main keys of success next to any talent and luck that anyone might be fortunate enough to have
39 min
December 14, 2022 Revisited: ”Featured Mentor’s Podcast: Andrea du Bois”
In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez, is joined by Professor Andrea du Bois. Prof du Bois completed his medical degree in 1987 at the University of Freiburg, Germany. He subsequently trained in general surgery at Krankenhaus Wolfach Personalwohnheim and gynaecology and obstetrics at the University of Freiburg, leading to his registration as Fellow for Gynaecology and Obstetrics in 1993.
In 1993, Prof. du Bois became a Consultant in the Department of Gynaecology and Obstetrics at St. Vincentius-Kliniken, Karlsruhe. He then served as Director of the Department of Gynaecology and Gynaecologic Oncology, Horst-Schmidt-Kliniken, Wiesbaden (1999-2010) before taking up his current roles as Director of the Department of Gynaecology and Gynaecologic Oncology at Kliniken Essen-Mitte, and Associate Professor at Johannes Gutenberg University of Mainz, Germany.
Prof. du Bois has been the Principal Investigator of several pivotal and practice-changing international clinical trials in gynaecological oncology. He founded the Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) Study Group in 1993 and co-founded the European Network of Gynaecological Oncological Trial groups (ENGOT) in 2007. He has previously been a member of the German Guideline Committee for guidelines in breast, cervical, and ovarian cancer, Chairman of the German quality assurance programme for ovarian cancer (QS-OVAR), and member of the Gynecological Cancer InterGroup (GCIG) executive board and European Society of Gynaecological Oncology (ESGO) council. Prof. du Bois has been Chairman and a member of the Scientific Committee of the Ovarian Cancer Consensus Conference of the GCIG, and served as a member of the Scientific Committee of the 1st European Society of Medical Oncology (ESMO)-ESGO Ovarian Cancer Consensus Conference 2018. Prof. du Bois is a member of the American Society of Clinical Oncology (ASCO), ESGO, International Gynecologic Cancer Society (ISGC), German Cancer Society, and AGO. He has authored more than 500 publications with more than 33,500 citations, and has a Google Scholar h index of 86.
Prof. du Bois has received multiple honours and awards in recognition for his work, including the Arthur Walpole Award (German Cancer Society, 2006), Ernst Wertheim Award (Austrian Society of Gynecologic Oncology, 2006), MD Anderson Madrid Lifetime Award (2016), Wilhelm-Warner Prize for Cancer Research (2019), German Cancer Prize (Deutsche Krebsgesellschaft, 2020) and honorary membership of the German Society for Gynecology and Obstetrics (2020); 2021 he received the ESGO Lifetime Achievement Award (European Society of Gynaecological Oncology).
41 min
December 12, 2022 Mentor’s Podcast: Anna Fagotti
In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez, is joined by Dr. Anna Fagotti. Dr. Fagotti is the director of the ovarian cancer unit at the A. Gemelli IRCCS University Hospital Foundation, ESGO President Elect and member of the ESGO Executive Committee, and Editor of the International Journal of Gynecological Cancer.
Highlights:
-Always practice your skills if you want to excel in minimally invasive surgery: Practice makes perfect.
-The journey is long for a gynecologic oncologist. We can’t foresee the future and plans might have to be adjusted along the way, so try to be flexible on what you have beside you. Try to answer the relevant clinical questions. Don’t create a question just to answer.
-There can be difficulties along the way, but look forward and focus on your aim and don’t get stopped by obstacles. Remember to try to enjoy everything.
25 min
November 28, 2022 Peritoneal Carcinomatosis after MIS in Cervical Cancer with Dr. Jorge Hoegl
In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez, is joined by Dr. Jorge Hoegl to discuss peritoneal carcinomatosis after minimally invasive surgery in cervical cancer. Dr. Jorge Hoegl is an early career gynecologic oncologist at the Department of Obstetrics and Gynecology at the General Hospital of the East “Dr. Domingo Luciani” in Caracas, Venezuela.
Highlights:
-Peritoneal carcinomatosis represented more than 15% of all recurrences, with a recurrence rate of 22.2% in minimally invasive surgery compared to 8.8%.
-Peritoneal carcinomatosis has been frequently grouped within distant recurrences and perhaps this made it not such a notorious fact.
-Peritoneal carcinomatosis does not appear to be an unusual recurrence pattern associated with cervical cancer and it should be reported separately.
24 min
November 21, 2022 SUCCOR: Validation of ESGO Quality Indicators Cervical Cancer with Félix Boria
In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez, is joined by Dr. Félix Boria to discuss the validation of ESGO quality indicators for cervical cancer. Mr. Boria is an attending physician of the gynecologic oncology division at the University of Navarra (Madrid, Spain) under the mentorship of Dr. Luis Chiva. He is currently finishing his PhD at Universidad Autonoma de Madrid about PET/CT and advanced ovarian cancer.
Highlights:
- Women who were operated on centers with high compliance of quality indicators had significant lower risk of relapse (HR, 0.39; 95% CI, 0.25 to 0.61; p- The rate of adjuvant treatment in Europe is surprisingly high, especially in low compliance centers (48%). Future investigations should try to address if we are overtreating patients with cervical cancer.
20 min

About IJGC Podcast

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The International Journal of Gynecological Cancer (IJGC) podcast explores the latest research on detection, prevention, diagnosis, and treatment of gynecologic malignancies. Enjoy interviews with leading experts as they discuss novel and relevant topics in the field of gynecologic cancer.