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🫀 Post-op AFib? Blame IL-6!
New @JClinInvest study shows IL-6 ➡️ STAT3 ➡️ CaMKII ➡️ RyR2 leak triggers post-op AFib.
🧬 Macrophage IL-6Rα is the match.
🧯 TTI-101 & KN-93 douse the flame.
⚡ Targeting IL-6 signaling = future Rx?
#CardioTwitter #AFib #Inflammation #JCI
By Dr RR Baliga, MD, MBA5
66 ratings
🫀 Post-op AFib? Blame IL-6!
New @JClinInvest study shows IL-6 ➡️ STAT3 ➡️ CaMKII ➡️ RyR2 leak triggers post-op AFib.
🧬 Macrophage IL-6Rα is the match.
🧯 TTI-101 & KN-93 douse the flame.
⚡ Targeting IL-6 signaling = future Rx?
#CardioTwitter #AFib #Inflammation #JCI

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